钟耀华教授
钟耀华，教授、博导，泰山产业领军人才，山东大学微生物技术国家重点实验室课题组长，挂任济南市投资促进局副局长。任山东省生物发酵产业协会常务理事、国际SCI期刊《Fermentation》编辑等。美国麻省理工学院博士后（2010年-2012年），并先后挂任山东省乐陵市人民政府副市长（2014年-2016年）和济南市历城区人民政府副区长（2019年-2020年）。主要从事工业真菌蛋白合成分泌机制与合成生物学研究、酶制剂和药用蛋白菌种研发以及食品微生物工程改良等。在Biotechnol Biofuels、Biores... More+
- [1] 张佳欣. An efficient CRISPR/Cas9 genome editing system based on a multiple sgRNA processing platform in Trichoderma reesei for strain improvement and enzyme production.. BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS, 17, 22, 2024.
- [2] 张佳欣. An efficient CRISPR/Cas9 genome editing system based on a multiple sgRNA processing platform in Trichoderma reesei for strain and enzyme production. BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS, 17, 22, 2024.
- [3] 万秀芬. Effective synthesis of high-content fructooligosaccharides in engineered Aspergillus niger. Microb Cell Fact., 23, 76, 2024.
- [4] 姚程. Overexpression of a Novel Vacuolar Serine Protease-Encoding Gene (spt1) to Enhance Cellulase Production in Trichoderma reesei.. FERMENTATION-BASEL, 191, 2023.
- [5] 姚程. The ERAD pathway participates in fungal growth and cellulase secretion in Trichoderma reesei. JOURNAL OF FUNGI, 74, 2023.
- [6] 孙雨. Development of a novel expression platform for heterologous protein production via deleting the p53-like regulator Vib1 in Trichoderma reese. ENZYME AND MICROBIAL TECHNOLOGY Journal, 109993, 2022.
- [7] 王璐. A novel sucrose-inducible expression system and its application for production of biomass-degrading enzymes in Aspergillus niger. BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS, 16, 2023.
- [8] . Enhancing the production of a heterologous Trametes laccase (LacA) by replacement of the major cellulase CBH1 in Trichoderma reesei.. Journal of Industrial Microbiology & Biotechnology, 1, 2023.
- [9] 郑芳林. Engineering Trichoderma reesei for Hyperproduction of Cellulases on Glucose to Efficiently Saccharify Pretreated Corncobs. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY Journal, 68, 12671, 2020.
- [10] 王玉波. Constitutive overexpression of cellobiohydrolase 2 in Trichoderma reesei reveals its ability to initiate cellulose degradation. Engineering Microbiology, 2022.
- [11] 钟耀华. Tailoring the expression of Xyr1 leads to efficient production of lignocellulolytic enzymes in Trichoderma reesei for improved saccharification of corncob residues. BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS, 15, 142, 2022.
- [12] 沈林静. Engineering the endoplasmic reticulum secretory pathway in Trichoderma reesei for improved cellulase production. ENZYME AND MICROBIAL TECHNOLOGY Journal, 152, 2021.
- [13] 钟耀华. Development of a novel expression platform for heterologous protein production via deleting the p53-like regulator Vib1 in Trichoderma reesei. Enzyme and Microbial Technology, 109993, 2022.
- [14] 孙雨. Extracellular protease production regulated by nitrogen and carbon sources in Trichoderma reesei. JOURNAL OF BASIC MICROBIOLOGY, 61, 122, 2021.
- [15] 张秀君. The complex Tup1-Cyc8 bridges transcription factor ClrB and putative histone methyltransferase LaeA to activate the expression of cellulolytic genes. Molecular Microbiology, 2022.
- [16] 王娟. Continuous production of fructooligosaccharides by recycling of the thermal-stable beta-fructofuranosidase produced by Aspergillus niger. Biotechnology Letters, 43, 1175, 2021.
- [17] 王逸凡. Development of a powerful synthetic hybrid promoter to improve the cellulase system of Trichoderma reesei for efficient saccharification of corncob residues. MICROBIAL CELL FACTORIES, 21, 2022.
- [18] 王琦. CRISPR/Cas9-mediated genome editing in Penicillium oxalicum and Trichoderma reesei using 5S rRNA promoter driven guide RNAs. Biotechnology Letters, 495, 2021.
- [19] 赵芹芹. Disruption of the Trichoderma reesei gul1 gene stimulates hyphal branching and reduces broth viscosity in cellulase production. Journal of Industrial Microbiology & Biotechnology, 48, 2021.
- [20] 王琦. CRISPR/Cas9-mediated genome editing inPenicillium oxalicumandTrichoderma reeseiusing 5S rRNA promoter-driven guide RNAs. BIOTECHNOLOGY LETTERS Journal, 2021.