Scientific Research
Working-Papers
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zhuang Jingjing, Tie Lu, Wu Dalei and Liu Qian.
Current strategies and progress for targeting the “undruggable” transcription factors.
Acta Pharmacologica Sinica,
43,
2474–2481,
2024.
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Chen Xiaoyu, Zhao Huilin, Wang Chuandong, Hamed Mostafa, Shang Qinghong, Yang Yating, Diao Xiaotong, Sun Xiangnan, Hu Wei, Jiang Xukai, Zhang Youming, Hirsch Anna K.H, Wu Dalei and Zhuang Jingjing.
Two natural compounds as potential inhibitors against the Helicobacter pylori and Acinetobacter baumannii IspD enzymes.
International Journal of Antimicrobial Agents,
2024.
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Zhuang Jingjing, Wu Dalei, Rastinejad Fraydoon and Shang Qinghong.
Decoding Allosteric Control in Hypoxia-Inducible Factors.
Journal of Molecular Biology,
2024.
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Ren Xintong, Diao Xiaotong, Zhuang Jingjing and Wu Dalei.
Structural Basis for the Allosteric Inhibition of Hypoxia-Inducible Factor 2 by Belzutifan.
Molecular pharmacology,
2023.
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Song Wanbin, Zhuang Jingjing, Zhang Nan, Ren Xintong, Xu Weiwei, Guo Mengqi, Diao Xiaotong, Liu Chao, Jin Jiaming, Wu Dalei and Zhang Yinan.
SAR study of 1,2-benzisothiazole dioxide compounds that agonize HIF-2 stabilization and EPO production br.
Bioorganic & medicinal chemistry,
77,
2023.
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孙向楠, 荆林倩, 李峰伟, 张美娜, 刁晓彤, 庄静静, Fraydoon Rastinejad and 武大雷.
Structures of NPAS4-ARNT and NPAS4-ARNT2 heterodimers reveal new dimerization modalities in the bHLH-PAS transcription factor family.
《PNAS》,
119,
2023.
Published Books
Research Projects
Research Team