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Lack of CUL4B leads to increased abundance of GFAP-positive cells that is mediated by PTGDS in mouse brain.

Release time:2019-04-14|Hits:

Affiliation of Author(s):基础医学院

Journal:Human Molecular Genetics

All the Authors:jiangbaichun,shaochangshun,Hu Huili,zouyongxin,lixi,jianghong

First Author:gongyaoqin

Indexed by:Unit Twenty Basic Research

Document Code:lw-169869

Volume:24

Issue:16

Page Number:4686

Translation or Not:no

Date of Publication:2015-08-15

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Replication stress induces micronuclei comprising of aggregated DNA double-strand breaks.
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Lack of Cul4b, an E3 ubiquitin ligase component, leads to embryonic lethality and abnormal placental development.

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