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CUL4B promotes replication licensing by up-regulating the CDK2-CDC6 cascade.

Release time:2019-10-24|Hits:

Affiliation of Author(s):基础医学院

Journal:J Cell Biol.

All the Authors:jiangbaichun,shaochangshun,zouyongxin

First Author:gongyaoqin

Indexed by:Unit Twenty Basic Research

Document Code:lw-143923

Volume:200

Issue:6

Page Number:743

Translation or Not:no

Date of Publication:2013-03-18

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Lack of CUL4B leads to increased abundance of GFAP-positive cells that is mediated by PTGDS in mouse brain.
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Lack of Cul4b, an E3 ubiquitin ligase component, leads to embryonic lethality and abnormal placental development.

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