【个人信息】

陈静，博士，副教授，硕士生导师。

    主要研究方向包括：微萃取-表面增强拉曼光谱联用技术、色谱质谱分离分析研究、污染溯源组学新方法研究等，入选中国分析测试协会专家库、中国色谱学会会员、山东省化学会环境化学与工程专业委员会成员、主持NSFC基金、山东省自然科学基金、江苏省自然科学基金、山东大学“未来学者”计划等项目、发表高水平期SCI论文30余篇，担任Cancer Endocrinology评审编辑以及Anal Chem.，Environ. Sci. Tech.，Food Chem., Sci. Total. Environm., Anal. Chim. Acta等国际学术期刊的特约审稿人。

【学习和工作经历】2016.10-今         山东大学化学与化工学院 副教授

• 2011.5-2016.9   美国宾夕法尼亚州立大学 博士后

• 2005.9-2011.4   中国科学院大连化学物理研究所 博士

• 2001.9-2005.7   南京大学  本科

【教学课程】

• 化学分析（本科生）

• 仪器分析（本科生）

• 仪器分析实验（本科生）

• 现代分离科学（研究生）

【研究方向】

• 色谱、质谱高分辨分离分析
  

• 微萃取-表面增强拉曼光谱联用技术

• 新兴有机微污染物\颗粒污染物的分析方法

  
  

【科研项目】

• 国家自然科学青年基金

• 山东省自然科学基金

• 江苏省自然科学基金

• 山东大学未来计划青年学者

• 山东大学基本科研业务费-人才引进项目

• 其他企事业单位委托项目

  
  

【研究论文】

25. T. Wang, S. Li, R. Mu, Z. Lu, J. Su, J Chen*, J. Zhan.  Size-Resolved SERS Detection of Trace Polystyrene Nanoplastics via Selective Electrosorption. Anal. Chem. 2024, accepted.

24. R. Mu, S. Li, T. Wang, Z. Lu, Q. Q, S. Cheng, D. Yu,  J. Zhan, J. Chen*. Electric Field Promoted Click Surface-Enhanced Raman Spectroscopy for Rapid and Specific Detection of DNA2‑Deoxyribose5′-Aldehyde Oxidation Products in Plasma. Anal. Chem. 2023, 95, 14324-14330.

23. S. Li, X. Lv, Q. Yang, S. Zhang, J. Su, S. Cheng, Y. Lai, J. Chen*, J. Zhan*, Dynamic SPME-SERS Induced by Electric Field: Towards In-situ Monitoring of Pharmaceuticals and Personal Care Products. Anal. Chem. 2022, 94, 9270-9277.

22. X. Lv, S. Li, Q.  Yang, S. Zhang, J. Su, S. Cheng, Y. Lai*, J. Chen*, J. Zhan,  Robust, reliable and quantitative sensing of aqueous arsenic species by Surface-enhanced Raman Spectroscopy: The crucial role of surface silver ions for good analytical practice. Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy, 2022, 281, 121600.

21. W. Lu, M. Yuan, J. Chen, J. Zhang, L. Kong, Z. Feng, X. Ma, J. Su, J.Zhan*, Synergistic Lewis acid-base sites of ultrathin porous Co₃O₄ nanosheets with enhanced peroxidase-like activity. Nano Research 2021, 14, 10, 3514-3522.

20. N. Li, M. Zhu, Z. Feng, W. Lu, J. Chen* and J. Zhan*, Carbon-nitrogen conjugate-composited Cu_1.8S with enhanced peroxidase-like activity for the colorimetric detection of hydrogen peroxide and glutathione. Anal. Methods 2021, 13, 14, 1706-1714.

19. W. Lu, J. Chen, L. Kong, F. Zhu, Z. Feng, J. Zhan*, Oxygen vacancies modulation Mn₃O₄ nanozyme with enhanced oxidase-mimicking performance for l-cysteine detection. Sensors and Actuators B-Chemical 2021, 333, 129560. 

18. Y. Song, H. C. Huang, W, Lu, N. Li, J. Su, S. B. Cheng, Y. Lai, J. Chen*, J. Zhan,  Ag@WS₂ quantum dots for Surface Enhanced Raman Spectroscopy: Enhanced charge transfer induced highly sensitive detection of thiram from honey and beverages. Food Chemistry 2021, 344, 128570. (Link)

17. N. Li, R. Li, Y. Song, L. Ma, C. Gao, L. Li, S. B. Cheng, X. Zhang, J. Chen* , J. Zhan, Caramelized carbonaceous shell-coated γ-Fe₂O₃ as a magnetic solid-phase extraction sorbent for LC-MS/MS analysis of triphenylmethane dyes. Microchimica Acta 2020, 187, 371. (Link)

16. W. Lu, J. Zhang, N. Li, Z. You, Z Feng, V. Natarajan, J. Chen, J. Zhan*, Co₃O₄@beta-cyclodextrin with synergistic peroxidase-mimicking performance as a signal magnification approach for colorimetric determination of ascorbic acid. Sensors and Actuators B-Chemical 2020, 303, 127106.  (Link)

15. S. Heller, N.K. Joshi*, J. Chen, E.G. Rajotte, C.A. Mullin, D.J. Biddinger, Pollinator exposure to systemic insecticides and fungicides applied in the previous fall and pre-bloom period in apple orchards. Environmental Pollution 2020, 265, 114589.

14. Y. Wang, X. Yu, Y. Chang, C. Gao, J. Chen*, X. Zhang* and J. Zhan*, A 3D spongy flexible nanosheet array for on-site recyclable swabbing extraction and subsequent SERS analysis of thiram. Microchimica Acta 2019, 186, 458. (Link)

13. H. Liu, N. Liu, W. Teng, J. Chen*, Study on a dSPE-LC-MS/MS method for lysophosphatidylcholines and underivatized neurotransmitters in rat brain tissues.  Journal of  Chromatography B 2018, 1096, 11-19.

12. J. Chen*, J. Fine, C. Mullin, Are organosilicon surfactants safe for bees or humans? Science of the Total Environment 2018, 612, 415-421.

11. C.A. Mullin*, J. Chen, J.D. Fine, M.T. Frazier, J.L. Frazier, The formulation makes the honey beepoison.  Pesticide Biochemistry and Physiology 2015, 120, 27-35.

10. J. Chen, C.A. Mullin*, Characterization of trisiloxane surfactants from agrochemical adjuvants and pollinator-related matrices using liquid chromatography coupled to mass spectrometry. Journal of Agricultural and Food Chemistry 2015, 63, 21, 5120-5125. 

9. J. Chen*, C.A. Mullin, Determination of nonylphenol ethoxylate and octylphenol ethoxylate surfactants in beehive samples by high performance liquid chromatography coupled to mass spectrometry.  Food Chemistry 2014, 158, 473-479.

8. J. Chen, C.A. Mullin*, Quantitative determination of trisiloxane surfactants in beehive environments based on liquid chromatography coupled to mass spectrometry. Environmental Science & Technology 2013, 47, 16, 9317-9323.  

7. J. Chen, L. Zhou, X. Zhang, X. Lu, R. Cao, C. Xu, G. Xu*, Urinary hydrophilic and hydrophobic metabolic profiling based on liquidchromatography-mass spectrometry methods: differential metabolite discovery specific to ovarian Cancer.  Electrophoresis 2012, 33. 3361-3369.

6. J. Chen, X. Zhang, R. Cao, X. Lu, S. Zhao, A. Fekete, Q. Huang, P. Schmitt-Kopplin, Y. Wang, Z. Xu, X. Wan,X. Wu, N. Zhao, C. Xu, G. Xu*, Serum 27-nor-5beta-cholestane-3,7,12,24,25 pentol glucuronide discovered by metabolomics as potential diagnostic biomarker for epithelium ovarian cancer. Journal of Proteome. Research 2011, 10. 2625-2632.

5. J. Chen, Y. Zhang, X. Zhang, R. Cao, S. Chen, Q. Huang, X. Lu, X. Wan, X. Wu, C. Xu, G. Xu*, Application of L-EDA in metabonomics data handling: global metabolite profiling and potential biomarkerdiscovery of epithelial ovarian cancer prognosis. Metabolomics 2011, 614-622.

4. J. Chen, W. Wang, S. Lv, P. Yin, X. Zhao, X. Lu, F. Zhang, G. Xu, Metabonomics study of liver cancer based on ultraperformance liquid chromatography coupled to mass spectrometry with HILIC and RPLC separations. Analytica Chimica Acta 2009, 650. 3-9.

3. J. Chen, Y. Shan, Q. Yan, S. Zhao, P. Yin, X. Zhao, X. Lu, X. Xi, X. Wan, G. Xu, A Metabonomics approach based onliquid chromatography-mass spectrometry: from metabolic profiling to potentialbiomarker. Science China-Chemistry 2009, 39. 1268-1276.

2. J. Chen, Y. Shan, X. Lu, X. Wan, G. Xu, Rapid quantification of serum bile acid profiles based on high performance liquid phase chromatography-mass spectrometry and its application in woman cervical cancer. Journal of Chinese Mass Spectrometry Society 2009, 30, 109-110.

1. J. Chen, X. Zhao, J. Fritsche, P. Yin, P. Schmitt-Kopplin, W. Wang, X. Lu, H. Haering, E.Schleicher, R. Lehmann, G. Xu, Practical approach for theidentification and isomer elucidation of biomarkers detected in a metabonomic study for the discovery of individuals at risk for diabetes by integrating the chromatographic and mass spectrometric information. Analytical Chemistry 2008, 80.1280-1289.

【专利】

   已授权专利：

1. 焦糖化碳纳米材料在去除水体中重金属的应用, 2021，专利号ZL202010522950.6

2. 一种磁性焦糖化碳纳米材料及其制备方法与应用, 2022，专利号ZL201911112507.5

3. 一种二硫化钨量子点包覆银纳米球的表面增强拉曼基底的制备方法与应用, 2022，专利号ZL202010995086.1
   

【学生情况及招生计划】

       课题组现有博士研究生1人、硕士研究生4人、本科生8人。

       课题组在读的每位研究生都有独立的项目。除学校和国家提供的补助外，课题组每年提供有竞争力的补助和奖励。无论你是继续读博深造还是毕业工作，我们课题组都是你值得选择的优秀平台。研究生就业范围：（1）高等院校或科研院所从事教学科研工作；（2）在政府部门、海关从事分析测试方面的管理工作；（3）在相关企业（药企、食品、烟草、酒）从事分析测试方面的工作。

Updated 2024/10/30：

• 2025年招收学术硕士1名！

       欢迎分析化学、药学、材料学等专业的同学。

• 2025年招收专业硕士1名！

       欢迎报考材料与化工、化学工程等专业的同学。

• 招收本科生到课题组学习！

       课题组所有本科生均有自己独立研究课题/体系，拥有相关成果的优先署名权。

【联系方式】

  地址：山东省济南市山大南路27号

           山东大学中心校区化学新楼345室

  E-mail: jingchen@sdu.edu.cn