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个人信息Personal Information
教授 博士生导师 硕士生导师
任职 : Aging，Cancer，Cancer Genetics，Oncology Letters，General Physiology and Biophysics ，Experimental and Therapeutic Medicine，Food & Function, Psychosomatic Medicine Research(Section Editor), 赣南医学院学报, 中国生物工程杂志，解剖科学进展
性别：男
毕业院校：清华大学
学历：研究生(博士)毕业
学位：博士生
在职信息：在职
所在单位：基础医学院
入职时间：2021-01-27
学科：遗传学
发育生物学
生物化学与分子生物学
办公地点：山东大学趵突泉校区电镜楼209
联系方式：zhezhang@sdu.edu.cn 课题组常年招聘助理教授，博士后；并欢迎博士生，硕士生，本科生报考和实习。
Oligonucleotide-based targeted gene editing in C. elegans via the CRISPR/Cas9 system
点击次数：
发表刊物：Cell research
摘要：Technologies to achieve specific and precise genome editing, such as knock-in and knock-out, are critical for deciphering the functions of a gene and for understanding fundamental biological processes. Compared with the zinc finger nucleases (ZFN) and transcription activator-like effector nucleases (TALEN), which have been used for genome editing, the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas) system has emerged as a new powerful tool for genome modifications. It has recently been adopted for genome editing in human cell lines, mouse, zebrafish, C. elegans, and plants.
全部作者：Hongmei Ke,Yiren Yue
第一作者：Pei Zhao#,张哲#
论文类型：期刊论文
通讯作者：Ding Xue*
论文编号：5
是否译文：否
发表时间：2014-02-01
收录刊物：SCI