ZHANG Lei
Professor
Prof. Lei Zhang is a distinguished professor at the School of Public Health, Shandong University. He is the director and principal investigator of the Microbiome-X center at the National Institute of Health Data Science of China, as well as the principal investigator at the State Key Laboratory of Microbial Technology, Shandong University. He also serves as the president of the Shandong Institute of Industrial Technology for Healthy Sciences a... More+
Scientific Research
Working-Papers
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Paper Publications
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张磊. Multiomics Analysis Reveals Aberrant Metabolism and Immunity Linked Gut Microbiota with Insomnia. MICROBIOLOGY SPECTRUM, 459, 2023.
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张磊. Stage-specific roles of microbial dysbiosis and metabolic disorders in rheumatoid arthritis. Annals of Rheumatic Diseases, 1669, 2023.
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张磊. Causal association between atopic eczema and inflammatory bowel disease: A two-sample bidirectional Mendelian randomization study of the East Asian population. JOURNAL OF DERMATOLOGY, 1, 2023.
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张磊. Pivotal interplays between fecal metabolome and gut microbiome reveal functional signatures in cerebral ischemic stroke. JOURNAL OF TRANSLATIONAL MEDICINE, 459, 2023.
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赵燕. Hidden link in gut–joint axis: gut microbes promote rheumatoid arthritis at early stage by enhancing ascorbate degradation. Gut, 1, 2022.
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赵璐. Putative Familial Transmissible Bacteria of Various Body Niches Link with Home Environment and Children’s Immune Health. Microbiology Spectrum, 2022.
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Putative familial transmissible bacteria of various body niches link with home environment and children's immune health, Microbiology Spectrum. 9, e00872-21, 2021.
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Hidden link in gut–joint axis: gut microbes promote rheumatoid arthritis at early stage by enhancing ascorbate degradation. Gut, 0, 1-2, 2021.
Patents
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肠道及口腔菌群多样性及差异性的分析方法，2018.03.06，ZL201710019639.8，中国发明专利
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Salivary Transcriptomic and Microbial Biomarkers for Pancreatic Cancer. 2018.11.20, US 10,132,811 B2，美国发明专利
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Salivary Biomarkers for Lung Cancer Detection. 2017.7.27, US 9,689,039 B2，美国发明专利
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Salivary Transcriptomic and Proteomic Biomarkers for Breast Cancer Detection. 2017.4.18, US 9,624,547 B2，美国发明专利
Published Books
Research Projects
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肠道微生物调控Sirt1/Kiss1介导肥胖诱导的性早熟机制研究, 2023-08-24-2027-12-31
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国家自然科学基金委员会，面上项目，82172320，跨代遗传的DNA甲基化异常通过“微生物-肠-脑轴”参与孤独症的调控机制研究，2022/01-2025/12，54万元
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山东大学2021年度国家重点研发计划拟培育项目，健康人微生物组基线及特征解析，15万元
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山东大学杰出中青年学者（第一层次）学科建设经费，人体微生物组研究，2021/01-2025/12，200万元
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山东省科学技术厅，山东省泰山产业领军人才项目，tscy20190612，肠道微生态产业化研究与产品开发，2020/01-2023/12，200万元
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山东省中央引导地方科技发展资金项目，免疫诊断检测技术创新平台，YDZX20193700002067，2019-2021，300万元
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山东省科学技术厅，山东省重大科技创新工程项目，2018CXGC1219，性早熟儿童肠道菌群精准评估及肠道微生态个性化干预体系，2018/01-2020/12，100万元
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山东省科学技术厅，山东省重大科技创新工程项目，2018CXGC1218，脂代谢异常患者肠道菌群的变化特征和标志物及其精准干预方案，2018/01-2020/12，110万元
Research Team
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