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个人信息Personal Information
副教授 硕士生导师
性别：男
毕业院校：中国科学院上海生命科学院生物化学与细胞生物学研究所
学历：研究生(博士)毕业
学位：博士生
在职信息：在职
所在单位：基础医学院
入职时间：2015-07-21
学科：人体解剖与组织胚胎学
免疫学
联系方式：lichunyang@sdu.edu.cn
电子邮箱：lichunyang@sdu.edu.cn
扫描关注
- [1] . Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8 + T cell exhaustion and anti-PD-1 resistance. CELL REPORTS MEDICINE, 5, 2024.
- [2] . Urolithin A Hijacks ERK1/2-ULK1 Cascade to Improve CD8+ T Cell Fitness for Antitumor Immunity. Advanced Science, 2024.
- [3] . Identification of a small-molecule Tim-3 inhibitor to potentiate T cell-mediated antitumor immunotherapy in preclinical mouse models. SCIENCE TRANSLATIONAL MEDICINE, 15, 2023.
- [4] 张言坤. ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury. NATURE COMMUNICATIONS, 14, 2023.
- [5] 秦丽萍. CRL4B complex-mediated H2AK119 monoubiquitination restrains Th1 and Th2 cell differentiation. Cell Death and Differentiation, 30, 1488-1502, 2023.
- [6] 丁璐. Zhx2 maintains islet β-cell mass and function by transcriptionally regulating Pax6. iScience, 26, 106871, 2023.
- [7] 王玉珍. TIM-4 orchestrates mitochondrial homeostasis to promote lung cancer progression via ANXA2/PI3K/AKT/OPA1 axis. 14, 2023.
- [8] 焦德雁. Lipid accumulation-mediated histone hypoacetylation drives persistent NK cell dysfunction in anti-tumor immunity. Cell Reports, 42, 2023.
- [9] 田盼盼. Early life gut microbiota sustains liver-resident natural killer cells maturation via the butyrate-IL-18 axis.. NATURE COMMUNICATIONS, 2023.
- [10] 王樱淳. Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages. cell reports, 2022.
- [11] 丁宇明. Intrinsic PD-L1 promotes antitumor activity of CD8+ cytotoxic T lymphocytes via in cis interaction with CD80.. CANCER COMMUNICATIONS, 42, 784, 2022.
- [12] 陈朝佳 , 彭加丽 , 马帅雅 , 丁宇明 , 黄涛 , 赵世刚 , 高立芬 , 梁晓红 , 李春阳 and 马春红. Ribosomal protein S26 serves as a checkpoint of T-cell survival and homeostasis in a p53-dependent manner. CELLULAR & MOLECULAR IMMUNOLOGY, 18, 1844, 2021.
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