山东大学教师主页刘博洋 Paper Publications Homepage

Boyang Liu Professor

刘博洋，男，内蒙古呼和浩特人，博士，山东大学附属生殖医院研究员、硕士生导师。山东省泰山学者青年专家，山东省优秀青年科学基金（海外）获得者。2016年毕业于德国哥廷根大学发育生物学专业，获自然科学博士学位。长期从事早期胚胎发育调控机制方面的研究，主要关注人类胚胎发育调控异常导致的妊娠失败和生殖障碍。累计发表SCI论文20余篇，承担国家重点研发计划项目1项、国家自然科学基金青年项目1项、山东省重点研发计划项目1项、山东省自然科学基金青年项目1项。现任国家自然科... More+

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[1] Keliang Wu , 张传鑫 , 田昊 and 陈子江. Crosstalk between H3K4me3 and oxidative stress is a potential target for the improvement of ART-derived embryos.. Nat Commun, 2025.
[2] 时永香. 童第周核质互作理论虚拟仿真实验课程及其智能体的创建. 生物学杂志, 2025.
[3] . Astaxanthin promotes in vitro maturation of mouse oocytes by regulating mitochondrial functions and protein homeostasis？. BIOLOGY OF REPRODUCTION Journal, 2025.
[4] . The asymmetric expression of HSPA2 in blastomeres governs the first embryonic cell-fate decision. Elife, 13, 2025.
[5] 史明泽. SHMT2 is essential for mammalian preimplantation embryonic development through de novo biosynthesis of nucleotide metabolites. MOLECULAR THERAPY-NUCLEIC ACIDS, 36, 2025.
[6] 张传鑫. 2-bromoacetamide exposure impairs oocyte maturation in mice and humans primarily via disrupting the cytoskeleton. Ecotoxicology and Environmental Safety, 272, 2024.
[7] 陈晓蕾. Calcium ionophore improves embryonic development and pregnancy outcomes in patients with previous developmental problems in ICSI cycles. BMC PREGNANCY AND CHILDBIRTH, 22, 2022.
[8] 吴克良. Proteomic analysis implicates that postovulatory aging leads to aberrant geneexpression, biosynthesis, RNA metabolism and cell cycle in mouse oocytes. JOURNAL OF OVARIAN RESEARCH, 2022.
[9] 宋劲竹. Functional substitution of zona pellucida with modified sodium hyaluronate gel in human embryos. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, 2022.
[10] Zou, Zhuoning. Translatome and transcriptome co-profiling reveals a role of TPRXs in human zygotic genome activation.. Science, eabo7923, 2022.
[11] 刘博洋. Temporal Gradients Controlling Embryonic Cell Cycle. BIOLOGY-BASEL, 10, 2021.
[12] 刘博洋. Fluorescence Fluctuation Analysis Reveals PpV Dependent Cdc25 Protein Dynamics in Living Embryos. PLOS Genetics, 16, 2020.
[13] 刘博洋. A Link between Deoxyribonucleotide Metabolites and Embryonic Cell-Cycle Control. Current Biology, 29, 2019.
[14] 刘博洋. The Role of dNTP Metabolites in Control of the Embryonic Cell Cycle. Cell Cycle, 18, 2019.
[15] 刘博洋. Multiple Functions of the Essential Gene PpV in Drosophila Early Development. G3-Genes Genomes Genetics, 9, 2019.
[16] 刘博洋. Link of Zygotic Genome Activation and Cell Cycle Control. Meth Mol Biol, 1605, 2017.

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Paper Publications

[1] Keliang Wu , 张传鑫 , 田昊 and 陈子江. Crosstalk between H3K4me3 and oxidative stress is a potential target for the improvement of ART-derived embryos.. Nat Commun, 2025.

[2] 时永香. 童第周核质互作理论虚拟仿真实验课程及其智能体的创建. 生物学杂志, 2025.

[3] . Astaxanthin promotes in vitro maturation of mouse oocytes by regulating mitochondrial functions and protein homeostasis？. BIOLOGY OF REPRODUCTION Journal, 2025.

[4] . The asymmetric expression of HSPA2 in blastomeres governs the first embryonic cell-fate decision. Elife, 13, 2025.

[5] 史明泽. SHMT2 is essential for mammalian preimplantation embryonic development through de novo biosynthesis of nucleotide metabolites. MOLECULAR THERAPY-NUCLEIC ACIDS, 36, 2025.

[6] 张传鑫. 2-bromoacetamide exposure impairs oocyte maturation in mice and humans primarily via disrupting the cytoskeleton. Ecotoxicology and Environmental Safety, 272, 2024.

[7] 陈晓蕾. Calcium ionophore improves embryonic development and pregnancy outcomes in patients with previous developmental problems in ICSI cycles. BMC PREGNANCY AND CHILDBIRTH, 22, 2022.

[8] 吴克良. Proteomic analysis implicates that postovulatory aging leads to aberrant geneexpression, biosynthesis, RNA metabolism and cell cycle in mouse oocytes. JOURNAL OF OVARIAN RESEARCH, 2022.

[9] 宋劲竹. Functional substitution of zona pellucida with modified sodium hyaluronate gel in human embryos. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, 2022.

[10] Zou, Zhuoning. Translatome and transcriptome co-profiling reveals a role of TPRXs in human zygotic genome activation.. Science, eabo7923, 2022.

[11] 刘博洋. Temporal Gradients Controlling Embryonic Cell Cycle. BIOLOGY-BASEL, 10, 2021.

[12] 刘博洋. Fluorescence Fluctuation Analysis Reveals PpV Dependent Cdc25 Protein Dynamics in Living Embryos. PLOS Genetics, 16, 2020.

[13] 刘博洋. A Link between Deoxyribonucleotide Metabolites and Embryonic Cell-Cycle Control. Current Biology, 29, 2019.

[14] 刘博洋. The Role of dNTP Metabolites in Control of the Embryonic Cell Cycle. Cell Cycle, 18, 2019.

[15] 刘博洋. Multiple Functions of the Essential Gene PpV in Drosophila Early Development. G3-Genes Genomes Genetics, 9, 2019.

[16] 刘博洋. Link of Zygotic Genome Activation and Cell Cycle Control. Meth Mol Biol, 1605, 2017.