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Discovery of Novel Diarylpyrimidine Derivatives as Potent HIV-1 NNRTIs Targeting the "NNRTI Adjacent" Binding Site

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Affiliation of Author(s):药学院

Journal:ACS MED CHEM LETT.

All the Authors:liuxinyong,zhanpeng,kangdongwei

First Author:liuxinyong

Document Code:B6866C7C1F4A43C0A5183C1EA8D2C69F

Translation or Not:no

Date of Publication:2018-02-27

Pre One:First discovery of a potential carbonate prodrug of NNRTI drug candidate RDEA427 with submicromolar inhibitory activity against HIV-1 K103N/Y181C double mutant strain.

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