location: Current position: Home >> Scientific Research >> Paper Publications

First discovery of a potential carbonate prodrug of NNRTI drug candidate RDEA427 with submicromolar inhibitory activity against HIV-1 K103N/Y181C double mutant strain.

Hits:

Affiliation of Author(s):药学院

Journal:Bioorg Med Chem Lett.

All the Authors:liuxinyong,kangdongwei,zhanpeng

First Author:liuxinyong

Document Code:E50576DDE35E43B7ACEE0E809B4D1981

Translation or Not:no

Date of Publication:2018-05-01

Pre One:Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant

Next One:Discovery of Novel Diarylpyrimidine Derivatives as Potent HIV-1 NNRTIs Targeting the "NNRTI Adjacent" Binding Site