本课题组主要从事纳米生物物理学这一交叉学科的研究，发展分子模拟理论，开展定量生物物理实验，探索纳米材料一系列生物效应的物理机制，解决纳米生物安全问题。开展纳米生物和医学材料研发，设计纳米抗菌和纳米原药材料。本课题组热忱欢迎有志从事科研工作的本科生、硕士研究生和博士研究生到课题组学习工作。欢迎具有物理、材料、或生物背景的同学报考。

本课题组强调理论与实验的结合，研究内容有：

①发展生物物理的理论与模拟方法，研究蛋白质、DNA等生命大分子的动力学演化、自组装和非线性行为，解释结构与功能关系；

②发展纳米生物复杂体系的物理模型，开展纳米生物效应与毒理性的机制研究，结合定量生物实验，解决纳米材料的生物安全性问题；

③结合理论和模拟，对自组装、量子效应和表面效应精确调控，理性研发纳米生物和医学材料，用于精准纳米药物制造。

代表性论文(统计到2018)：

实时更新请移步https://faculty.sdu.edu.cn/lwf/zh_CN/lwcg/799314/list/index.htm

1.    Weifeng Li, Yanmei Yang, Gang Zhang and Yong-Wei Zhang, "Ultrafast and directional diffusion of lithium in phosphorene for high-performance lithium-ion battery", Nano Lett., 2015, 15, 1691-1697

2.    Weifeng Li, Yanmei Yang, Jeffrey K. Weber, Gang Zhang and Ruhong Zhou, "Tunable, Strain-Controlled Nanoporous MoS2 Filter for Water Desalination", ACS Nano, 2016, 10, 1829-1835.

3.    Ge Fang, Weifeng Li（共同一作）, Xiaomei Shen, Jose Manuel Perez-Aguilar, Yu Chong, Xingfa Gao, Zhifang Chai, Chunying Chen, Cuicui Ge and Ruhong Zhou, " Differential Pd-nanocrystal facets demonstrate distinct antibacterial activity against Gram-positive and Gram-negative bacteria", Nature Communications, 2018, 9, 129

4.      Zonglin Gu, Lin Zhao, Shengtang Liu, Guangxin Duan, Jose Manuel Perez-Aguilar, Judong Luo, Weifeng Li* and Ruhong Zhou, "Orientational Binding of DNA Guided by the C2N Template", ACS Nano, 2017, 11, 3198-3206.

5.    Zhiwei Zhao, Rong Yan, Xuan Yi, Jingling Li, Jiaming Rao, Zhengqing Guo, Yanmei Yang, Weifeng Li*, Yong-Qiang Li and Chunying Chen, "Bacteria-Activated Theranostic Nanoprobes against Methicillin-Resistant Staphylococcus aureus Infection", ACS Nano, 2017, 11, 5, 4428-4438

6.    Baoyu Li, Weifeng Li*, Jose Manuel Perez-Aguilar and Ruhong Zhou, "Mild Binding of Protein to C2N Monolayer Reveals Its Suitable Biocompatibility", Small, 2017, 1603685.

7.    Rui Shi, Xing Dai, Weifeng Li（共同一作）, Fang Lu, Yang Liu, Huihua Qu, Hao Li, Qiongyang Chen, He Tian and Enhui Wu, "Hydroxyl-Group-Dominated Graphite Dots Reshape Laser Desorption/Ionization Mass Spectrometry for Small Biomolecular Analysis and Imaging", ACS Nano, 2017, 11, 9500-9513.

8.    Xiuxiu Wang, Baoyu Li, David R. Bell, Weifeng Li* and Ruhong Zhou, "Hydrogen and methane storage and release by MoS2 nanotubes for energy storage", J. Mater. Chem. A, 2017, 5, 23020-23027.

9.    Weifeng Li, Meng Guo, Gang Zhang and Yong-Wei Zhang, "Edge-Specific Au/Ag Functionalization-Induced Conductive Paths in Armchair MoS2 Nanoribbons", Chem. Mater., 2014, 26, 5625–5631

10.  Weifeng Li, Lushan Wang, Ruhong Zhou and Yuguang Mu, "Ionic Liquid Induced Inactivation of Cellobiohydrolase I from Trichoderma Reesei", Green Chem., 2014.

11.  Weifeng Li, Gang Zhang, Meng Guo and Yong-Wei Zhang, "Strain-tunable electronic and transport properties of MoS2 nanotubes", Nano Res., 2014, 7, 1-10.

12.  Weifeng Li and Yuguang Mu, "Dissociation of hydrophobic and charged nano particles in aqueous guanidinium chloride and urea solutions: A molecular dynamics study", Nanoscale, 2012, 4, 1154-1159.

13.  Weifeng Li, Xing Dai, Joseph Morrone, Gang Zhang and Ruhong Zhou, "Thickness dependent semiconductor-to-metal transition of two-dimensional polyaniline with unique work functions", Nanoscale, 2017, 9, 12025-12031.

14.  Weifeng Li, Lars Nordenskiold, Ruhong Zhou and Yuguang Mu, "Conformation-dependent DNA attraction", Nanoscale, 2014, 6, 7085-7092.

15.  Weifeng Li, Mingwen Zhao, Yueyuan Xia, Ruiqin Zhang and Yuguang Mu, "Covalent-adsorption induced magnetism in graphene", J. Mater. Chem., 2009, 19, 9274-9282.

16.  Huihao Xia, Weifeng Li, You Song, Xinmei Yang, Xiangdong Liu, Mingwen Zhao, Yueyuan Xia, Chen Song, Tian-Wei Wang, Dezhang Zhu, Jinlong Gong and Zhiyuan Zhu, "Tunable Magnetism in Carbon-Ion-Implanted Highly Oriented Pyrolytic Graphite", Adv. Mater. (Weinheim, Ger.), 2008, 20, 4679-4683.

17.  Meng Guo, Yanmei Yang, Yanhua Leng, Li Wang, Huomin Dong, Hong Liu and Weifeng Li*, "Edge dominated electronic properties of MoS2/graphene hybrid 2D materials: edge state, electron coupling and work function", Journal of Materials Chemistry C, 2017, 5, 4845-4851

18.  Xu Liu, Guangxin Duan, Weifeng Li*, Zhufa Zhou and Ruhong Zhou, "Membrane destruction-mediated antibacterial activity of tungsten disulfide (WS2)", RSC Advances, 2017, 7, 37873-37880.

19.  Zonglin Gu, Weifeng Li*, Linbi Hong and Ruhong Zhou, "Exploring biological effects of MoS2 nanosheets on native structures of α-helical peptides", J. Chem. Phys., 2016, 144, 175103.

20.  Weifeng Li, Meng Guo, Gang Zhang and Yong-Wei Zhang, "Gapless MoS₂ allotrope possessing both massless Dirac and heavy fermions", Phys. Rev. B, 2014, 89, 205402.

21.  Weifeng Li, Gang Zhang and Yong-Wei Zhang, "Electronic Properties of Edge-Hydrogenated Phosphorene Nanoribbons: A First-Principles Study", J. Phys. Chem. C, 2014, 118, 22368-22372.

22.  Shuang Zhang, Jiong Yang, Renjing Xu, Fan Wang, Weifeng Li, Muhammad Ghufran, Yong-Wei Zhang, Zongfu Yu, Gang Zhang and Qinghua Qin, "Extraordinary photoluminescence and strong temperature/angle-dependent Raman responses in few-layer phosphorene", ACS Nano, 2014, 8, 9590-9596.

23.  Weifeng Li, Ruhong Zhou and Yuguang Mu, "Salting Effects on Protein Components in Aqueous NaCl and Urea Solutions: Toward Understanding of Urea-Induced Protein Denaturation", J. Phys. Chem. B, 2012, 116, 1446-1451.

24.  Peng Li, Yin Fun Poon, Weifeng Li, Hong-Yuan Zhu, Siew Hooi Yeap, Ye Cao, Xiaobao Qi, Chuncai Zhou, Mouad Lamrani, Roger W. Beuerman, En-Tang Kang, Yuguang Mu, Chang Ming Li, Matthew W. Chang, Susanna Su Jan Leong and Mary B. Chan-Park, "A polycationic antimicrobial and biocompatible hydrogel with microbe membrane suctioning ability", Nat. Mater., 2011, 10, 149-156

25.  Weifeng Li and Yuguang Mu, "Hydration patterns and salting effects in sodium chloride solution", J. Chem. Phys., 2011, 135, 134502-134506.

26.  Weifeng Li, Lars Nordenski?ld and Yuguang Mu, "Sequence-Specific Mg2+–DNA Interactions: A Molecular Dynamics Simulation Study", J. Phys. Chem. B, 2011, 115, 14713-14720.

27.  Weifeng Li, Mingwen Zhao, Tao He, Chen Song, Xiaohang Lin, Xiangdong Liu, Yueyuan Xia and Liangmo Mei, "Concentration dependent magnetism induced by hydrogen adsorption on graphene and single walled carbon nanotubes", J. Magn. Magn. Mater., 2010, 322, 838-843.

28.  Weifeng Li, Mingwen Zhao, Xian Zhao, Yueyuan Xia and Yuguang Mu, "Hydrogen saturation stabilizes vacancy-induced ferromagnetic ordering in graphene", Phys. Chem. Chem. Phys., 2010, 12, 13699-13706.

29.  Weifeng Li, Mingwen Zhao, Yueyuan Xia, Tao He, Chen Song, Xiaohang Lin, Xiangdong Liu and Liangmo Mei, "Silver-filled single-walled carbon nanotubes: Atomic and electronic structures from first-principles calculations", Phys. Rev. B, 2006, 74, 195421.