Ø     新的寡糖化学合成方法的发展。

Ø     生物活性寡糖(肿瘤,病毒,细菌相关糖抗原)的合成及药物活性评价。

Ø         以糖类化合物为基础的抗癌疫苗的研制(设计,合成及评价)。

1.       Tong Li, Tianlu Li, Tongxiao Cui, Yajing Sun, Fengshan Wang, Hongzhi Cao, Richard R. Schmidt*, Peng Peng* Regioselective One-Pot Benzoylation of Triol and Tetraol Arrays in Carbohydrates. Org. Lett. 2018, 20, 3862-3865.

2.       Peng Peng, Richard R. Schmidt* Acid–Base Catalysis in Glycosidations: A Nature Derived Alternative to the Generally Employed Methodology. Acc. Chem. Res. 2017, 50, 1171-1183.

3.       Peng Peng, Michael Linseis, Rainer F. Winter and Richard R. Schmidt* Regioselective Acylation of Diols and Triols: The Cyanide Effect J. Am. Chem. Soc. 2016, 138, 6002-6009.

4.       Peng Peng and Richard R. Schmidt* An Alternative Reaction Course in O-glycosidation with O-glycosyl Trichloroacetimidates as Glycosyl Donors and Lewis Acidic Metal Salts as Catalyst: Acid-Base Catalysis with Gold Chloride-Glycosyl Acceptor Adducts J. Am. Chem. Soc. 2015, 137, 12653-12659.

5.       Peng Peng, Yiqun Geng, Göttker-Schnetmann, Inigo and Richard R. Schmidt* 2-Nitro-thioglycosides: α- and β-Selective Generation and Their Potential as β-Selective Glycosyl Donors Org. Lett. 2015, 17, 1421-1424.

6.       Peng Peng, Han Liu, Jianzhi Gong, John M. Nicholls, Xuechen Li* A Facile Synthesis of Sialylated Oligolactosamine Glycans from Lactose via the Lafont Intermediate Chem. Sci. 2014, 5, 3634-3639.

7.       Peng Peng, De-Cai, Xiong, Xin-Shan Ye* Ortho-Methylphenylthioglycosides as Glycosyl Building Blocks for Preactivation-based Oligosaccharide Synthesis Carbohydr. Res. 2014, 384, 1-8.

8.       Peng Peng, Xin-Shan Ye* O,O-Dimethylthiophosphonosulfenyl Bromide-silver Triflate: a New Powerful Promoter System for the Preactivation of Thioglycosides Org. Biomol. Chem. 2011, 9, 616-622.

9.       Ye Jinfeng, Liu Xian -Wei, Peng Peng, Yi Wen, Chen Xi, Wang Fengshan, Cao Hong Zhi* Diversity-Oriented Enzymatic Modular Assembly of ABO Histo-blood Group Antigens. ACS Catal. 2016, 6, 8140-8144.