Alginate, Alginate lyase, Alginate-utilising systems, Application of alginate lyases, Metabolic engineering
Brown macroalgae have attracted great attention as an alternative feedstock for biorefining. Although direct conversion of ethanol from alginates (major components of brown macroalgae cell walls) is not amenable for industrial
production, significant progress has been made not only on enzymes involved in alginate degradation, but also on
metabolic pathways for biorefining at the laboratory level. In this article, we summarise recent advances on four
aspects: alginate, alginate lyases, different alginate-degrading systems, and application of alginate lyases and associated pathways. This knowledge will likely inspire sustainable solutions for further application of both alginate lyases
and their associated pathways.