张颖杰
个人信息Personal Information
副教授 博士生导师 硕士生导师
性别:男
毕业院校:山东大学
学历:研究生(博士)毕业
学位:医学博士学位
在职信息:在职
所在单位:药学院
入职时间:2013-02-28
电子邮箱:zhangyingjie@sdu.edu.cn
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- [21] 徐文方 , 张颖杰 and 曹江营. Leucine ureido derivatives as aminopeptidase N inhibitors using click chemistry. Part II. BIOORGANIC & MEDICINAL CHEMISTRY Journal, 27, 978, 2019.
- [22] 徐文方 , 张颖杰 and 梁学武. Discovery of Novel Janus Kinase (JAK) and Histone Deacetylase (HDAC) Dual Inhibitors for the Treatment of Hematological Malignancies. 《Journal of Medicinal Chemistry》, 62, 3898, 2019.
- [23] 徐文方 , 张颖杰 and 陈奉泉. Progress of CDK4/6 inhibitor palbociclib in the treatment of cancer. Anti-cancer agents in medicinal chemistry, 2018.
- [24] 徐文方 , 张颖杰 and 赵春龙. Discovery of meta-sulfamoyl N-hydroxybenzamides as HDAC8 selective inhibitors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 150, 282, 2018.
- [25] 徐文方 , 张颖杰 and 臧杰. Discovery of Novel Pazopanib-Based HDAC and VEGFR Dual Inhibitors Targeting Cancer Epigenetics and Angiogenesis Simultaneously. Journal of Medicinal Chemistry, 61, 5304, 2018.
- [26] 张颖杰 , 徐文方 and 江余祺. Synthesis and biological characterization of ubenimex-fluorouracil conjugates for anti-cancer therapy. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 143, 334, 2018.
- [27] 徐文方 , 张颖杰 and 高倩文. JAK/STAT Signal Transduction: Promising Attractive Targets for Immune, Inflammatory and Hematopoietic Diseases. Current Drug Targets, 19, 487, 2018.
- [28] 张颖杰 , 徐文方 and 曹江营. Design, Synthesis, and Biological Evaluation of Pyrazoline-Based Hydroxamic Acid Derivatives as AminopeptidaseN (APN) Inhibitors. CHEMMEDCHEM, 13, 431, 2018.
- [29] 徐文方 , 张颖杰 and 臧杰. Development of N-hydroxycinnamamide-based HDAC inhibitors with improved HDAC inhibitory activity and in vitro antitumor activity. Bioorganic & medicinal chemistry, 25, 2666, 2017.
- [30] 徐文方 , 张颖杰 and 高帅. Design, synthesis and anti-tumor activity study of novel histone deacetylase inhibitors containing isatin-based caps and o-phenylenediamine-based zinc binding groups. Bioorganic & medicinal chemistry, 25, 2981, 2017.
- [31] 杨新颖 , 徐文方 , 张颖杰 and 闫玉刚. Sulfoxide Analogs of TAK-875 as G Protein Coupled Receptor 40 Agonists: Synthesis, Determination of Absolute Configuration and Biological Activity. Chinese journal of organic chemistry, 37, 858, 2017.
- [32] 徐文方 , 张颖杰 , 吴敬德 and 李晓杨. Selective HDAC inhibitors with potent oral activity against leukemia and colorectal cancer: Design, structure-activity relationship and anti-tumor activity study. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 134, 185, 2017.
- [33] 徐文方 , 张颖杰 and 周楠. Discovery of a tetrahydroisoquinoline-based HDAC inhibitor with improved plasma stability. Bioorganic & medicinal chemistry, 25, 4614, 2017.
- [34] 张颖杰. Discovery of a fluorescent probe with HDAC6 selective inhibition. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 141, 596, 2017.
- [35] 徐文方 , 张颖杰 and 高帅. Preclinical and Clinical Studies of Chidamide (CS055/HBI-8000), An Orally Available Subtype-selective HDAC Inhibitor for Cancer Therapy. Anti-cancer agents in medicinal chemistry, 17, 802, 2017.
- [36] 张颖杰 and 徐文方. Nitric oxide donor hybrid compounds as promising anticancer agents. Drug Discov. Ther., 2016.
- [37] 张颖杰 and 徐文方. Design, synthesis, and antitumor evaluation of histone deacetylase inhibitors with L-phenylglycine scaffold. Drug Des. Dev. Ther., 2015.
- [38] 张颖杰 and 徐文方. Design, Synthesis and Antitumor Evaluation of Novel Histone Deacetylase (HDAC) Inhibitors Equipped with Phenylsulfonylfuroxan Module as Nitric Oxide (NO) Donor. J. Med. Chem., 2015.
- [39] 张颖杰. Novel leucine ureido derivatives as aminopeptidase N inhibitors. Design, synthesis and activity evaluation. Eur. J. Med. Chem., 2016.
- [40] 徐文方 , 张颖杰 and 刘新泳. Discovery of N-Substituted Oseltamivir Derivatives as Potent and Selective Inhibitors of H5N1 Influenza Neuraminidase. J. Med. Chem, 2014.