Zhe Zhang

Professor   Supervisor of Doctorate Candidates   Supervisor of Master's Candidates

Name (Simplified Chinese):张哲

Name (English):Zhe Zhang

Name (Pinyin):Zhang Zhe

Date of Employment:2021-01-27

School/Department:School of Basic Medical Sciences

Administrative Position:Professor

Education Level:Postgraduate (Doctoral)

Business Address:Room 209, Electron Microscopy Building, No.44 Wenhua Xi Road,
Shandong University School of Basic Medical Sciences, Ji'nan, Shandong
250012, P.R.China

Gender:Male

Contact Information:

Degree:Doctor

Status:Employed

Other Post:Aging,Cancer,Cancer Genetics,Oncology Letters,General Physiology and Biophysics ,Experimental and Therapeutic Medicine,Food & Function, Psychosomatic Medicine Research(Section Editor), Current Pharmaceutical Biotechnology, 赣南医学院学报, 中国生物工程杂志,解剖科学进展

Alma Mater:Tsinghua University

College:Cheeloo College of Medicine

Discipline:Genetics
Developmental Biology
Biochemistry and Molecular Biology


Paper Publications

Oligonucleotide-based targeted gene editing in C. elegans via the CRISPR/Cas9 system

Hits:

Title of Paper:Oligonucleotide-based targeted gene editing in C. elegans via the CRISPR/Cas9 system

Journal:Cell research

Summary:Technologies to achieve specific and precise genome editing, such as knock-in and knock-out, are critical for deciphering the functions of a gene and for understanding fundamental biological processes. Compared with the zinc finger nucleases (ZFN) and transcription activator-like effector nucleases (TALEN), which have been used for genome editing, the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas) system has emerged as a new powerful tool for genome modifications. It has recently been adopted for genome editing in human cell lines, mouse, zebrafish, C. elegans, and plants.

First Author:Pei Zhao#,Zhe Zhang#

Correspondence Author:Ding Xue*

All the Authors:Hongmei Ke,Yiren Yue

Document Code:5

Impact Factor:20.51

DOI Number:10.1038/cr.2014.9

Translation or Not:No

Date of Publication:2014-02

Included Journals:SCI

Release Time:2014-02-01