方诩
教授
所属院部: 微生物技术研究院
访问次数:
基本信息
  • 教师英文名称:
    Xu Fang
  • 教师拼音名称:
    fangxu
  • 电子邮箱:
    fangXu@sdu.edu.cn
  • 入职时间:
    2009-06-02
  • 所在单位:
    微生物技术研究院
  • 职务:
  • 学历:
    研究生(博士)毕业
  • 办公地点:
    山东省青岛市即墨区鳌山卫镇滨海大道72号山东大学青岛校区N1号楼237房间
  • 性别:
  • 学位:
    博士
  • 在职信息:
    在职
  • 其他任职:
    济南市政协委员
  • 毕业院校:
    日本京都大学
  • 博士生导师
  • 硕士生导师
学科:
生物工程;
生物化工;
微生物学;
发酵工程;
教师简介

现任山东大学微生物技术国家重点实验室、国家糖工程技术研究中心教授兼博士生导师、欧美同学会(中国留学人员联谊会)留日分会理事,济南市留学人员联谊会副会长,济南市政协委员、山东省循环经济协会副秘书长、中国可再生能源学会生物质能专业委员会常委、中国草学会能源草类专业委员会副理事长、中国生物发酵产业协会微生物育种分会理事、山东省高层次人才发展促进会现代农业专业委员会委员等职。先后入选教育部新世纪优秀人才,泰山产业领军人才。曾任山东省秸秆生物炼制技术重点实验室主任。获得国内外20项以上发明专利授权。荣获“山东青年五四奖章”、国家技术发明二等奖、生物工程学报优秀论文奖、山东省留学人员回国创业奖、中国轻工业联合会科技进步奖三等奖、山东省循环经济十大创新科技成果、中国循环经济协会科学技术二等奖等奖项。

研究方向为生物技术,长期致力于木质纤维素等生物质生物降解以及高值化利用。先后主持和参与国家重点研发计划、863计划、973计划、国家科技支撑计划、国家自然科学基金和山东省重大专项等。至今发表了70篇以上的论文,其中SCI论文50篇以上,作为主编编著了Springer-nature出版社出版的英文专著《Fungal Cellulolytic Enzymes: Microbial Production and Application》,并且为三本中英文专著编写了章节。本课题组在过去十年中,研究经费高达一千万元,仅2019年,获得各项研究经费500万元。 多项科研成果成功产业化,应用在山东省和江苏省的企业。并且和日本京都大学、产业综合研究所等国外著名机构进行合作研究。

教育经历
  • 2003-4-至今
    日本国立京都大学
    食品生物科学
    农学博士学位
  • 2001-4-至今
    日本国立京都大学
    生物科学与技术
    硕士
  • 1991-9 — 1995-7
    天津商学院
    食品工程
    学士
  • 1989-9-至今
    广西南宁第三中学
工作经历
  • 2009-5-至今
    山东大学生命科学学院
  • 2006-5 — 2009-4
    日本国立产综研生物质中心
  • 1995-7 — 1999-1
    广西大学
研究领域

微生物代谢工程、合成生物学、生物催化

科研成果
论文

1.  韩丽娟. Redesigning transcription factor Cre1 for alleviating carbon catabolite repression in Trichoderma reesei.  Synth Syst Biotechnol,  5,  230, 2020. 

2.  韩丽娟. Precision Engineering of the Transcription Factor Cre1 inHypocrea jecorina(Trichoderma reesei) for Efficient Cellulase Production in the Presence of Glucose.  Frontiers in Bioengineering and Biotechnology,  8,  2020. 

3.  蒋艺. Gluconic Acid Production from Potato Waste by Gluconobacter oxidans Using Sequential Hydrolysis and Fermentation.  ACS SUSTAINABLE CHEMISTRY & ENGINEERING,  5,  6116, 2017. 

4.  李岩. Two-phase anaerobic digestion of lignocellulosic hydrolysate: Focusing on the acidification with different inoculum to substrate ratios and inoculum sources.  Science of the Total Environment,  699,  2020. 

5.  牛康乐. A novel strategy for efficient disaccharides synthesis from glucose by beta-glucosidase.  BIORESOURCES AND BIOPROCESSING,  7,  2020. 

6.  蒋艺. 木质纤维素降解酶生产菌株的遗传改造及应用.  《微生物学报》,  57,  1235, 2017. 

7.  方诩. Lacto-N-biose synthesis via a modular enzymatic cascade with ATP regeneration.  iScience,  102236, 2021. 

8.  郭伟. Rewiring central carbon metabolism for tyrosol and salidroside production in Saccharomyces cerevisiae.  Biotechnology and Bioengineering,  2020. 

9.  陈志刚 , 杜志强 , 沈煜  and 方诩. Rewiring central carbon metabolism for tyrosol and salidroside production in Saccharomyces cerevisiae.  Bioengineering and Biotechnology,  2020. 

10.  方诩. Acidogenic and methanogenic properties of corn straw silage: Regulation and microbial analysis of two-phase anaerobic digestion.  Bioresource technology,  307,  123180, 2020. 

11.  沈煜 , 谷立川  and 方诩. Identification and characterization of an efficient D-xylose transporter in Saccharomyces cerevisiae.  Journal of Agricultural and Food Chemistry,  68,  2702, 2020. 

12.  方诩 , 刘玉翠  and 贾春江. Use of fusion transcription factors to reprogram cellulase transcription and enable efficient cellulase production in Trichoderma reesei.  Biotechnology for Biofuels,  2019. 

13.  方诩. Exploring the relationship between Clostridium thermocellum JN4 and Thermoanaerobacterium thermosaccharolyticum GD17.  Frontiers in Microbiology,  2019. 

14.  倪寿清 , 徐世平 , 方诩 , 占金华  and 张烁烁. One-pot synthesis of highly active Ni/Fe nano-bimetal by simultaneous ball milling and in situ chemical deposition.  RSC Advances,  41,  26469, 2018. 

15.  方诩  and 沈煜. Rational Engineering of Chorismate-Related Pathways in Saccharomyces cerevisiae for Improving Tyrosol Production.  Frontiers in Bioengineering and Biotechnology,  7,  152, 2019. 

16.  方诩. N2O emission and bacterial community dynamics.  RSC advances,  2018. 

17.  方诩. Identification of a thermostable fungal lytic polysaccharide monooxygenase and evaluation of its effect on lignocellulosic degradation.  Applied Microbiology and Biotechnology,  103,  5739, 2019. 

18.  方诩 , 王明钰  and 戴莉. The structural and biochemical basis for cellulose biodegradation.  Journal of Industrial Technology and Biotechnology,  88,  491, 2013. 

19.  方诩  and 曲音波. Long-term strain improvements accumulate mutations in regulatory elements responsible for hyper-production of cellulolytic enzymes.  scientific reports,  2013. 

20.  方诩 , 王明钰  and 侯少莉. 里氏木霉纤维素酶生产工艺的优化.  黑龙江农业科学,  2012,  108, 2012. 

21.  方诩 , 王明钰  and 王方忠. Regulation of cellulase expression, sporulation and morphogenesis by velvet family proteins in Trichoderma reesei.  Applied Microbiology and Biotechnology,  100,  769, 2016. 

22.  王明钰 , 贾春江 , 方诩  and Yong Yi. An environmentally friendly and productive process for bioethanol production from potato waste.  Biotechnology for Biofuels,  9,  50, 2016. 

23.  方诩 , 曲音波 , 王禄山  and 王明钰. Cellulolytic enzyme production and enzymatic hydrolysis for second-generation biofuel production.  Advances in Biochemical Engineering-Biotechnology,  128,  1, 2012. 

24.  方诩 , 王明钰  and 张杰. Efficient acetone-butanol-ethanol production from corncob with a new pretreatment technology - wet disk milling.  Bioenergy Research,  6,  35, 2013. 

25.  方诩 , 王明钰  and 王俊丽. The identification of and relief from Fe3+ inhibition for both cellulose and cellulase in cellulose saccharification catalyzed by cellulases from Penicillium decumbens.  Bioresource Technology,  133,  507, 2013. 

26.  方诩 , 杨静华 , 王明钰  and 姜宝杰. A mitogen-activated protein kinase Tmk3 participates in high osmolarity resistance, cell wall integrity maintenance and cellulase production regulation in Trichoderma reesei.  PLoS ONE,  8,  e72189, 2013. 

27.  方诩 , 王明钰  and 自振滔. 利用等离子诱变技术改造纤维素酶生产丝状真菌工业菌株.  中国酿造,  32,  5, 2013. 

28.  方诩 , 王明钰  and 杨惠. Functional diversity of the p24γ homologue Erp reveals physiological differences between two filamentous fungi.  Fungal Genetics and Biology,  61,  15, 2013. 

29.  邵明 , 徐孝刚 , 方诩 , 沈煜 , 魏天迪  and 王明钰. 山东大学生物类拔尖人才培养模式的探索.  高校生物学教学研究(电子版),  3,  3, 2013. 

30.  方诩 , 王明钰  and 王方忠. 丝状真菌中纤维素酶与半纤维素酶的合成调控.  生物加工过程,  12,  72, 2014. 

31.  方诩 , 王明钰  and 张晓东. 以木质纤维素原料生产生物丁醇的研究进展.  生物产业技术,  2014,  59, 2014. 

32.  曲音波 , 方诩 , 李雪芝  and 林建强. High concentration ethanol production from corncob residues by fed-batch strategy.  Bioresource technology,  101,  4952, 2010. 

33.  王明钰 , 沈煜 , 徐孝刚 , 邵明 , 魏天迪  and 方诩. 山东大学生物类拔尖人才培养模式的探索.  高校生物学教学研究(电子版),  3,  3, 2013. 

34.  王明钰 , 方诩  and 自振滔. 利用等离子诱变技术改造纤维素酶生产丝状真菌工业菌株.  中国酿造,  32,  5, 2013. 

35.  倪寿清 , 占金华 , 徐世平 , 方诩 One-pot synthesis of highly active Ni/Fe nano-bimetal by simultaneous ball milling and in situ chemical deposition.  RSC Advances,  2018. 

36.  王明钰  and 方诩. Role of Trichoderma reesei mitogen-activated protein kinases (MAPKs) in cellulase formation.  Biotechnology for biofuels,  10,  99, 2017. 

37.  方诩 , 倪寿清  and 徐世平. One-pot synthesis of highly active Ni/Fe nano-bimetal by simultaneous ball milling and in situ chemical deposition.  RSC advances,  2018. 

38.  沈煜  and 方诩. Rational Engineering of Chorismate-Related Pathways in Saccharomyces cerevisiae for Improving Tyrosol Production.  Frontiers in Bioengineering and Biotechnology,  7,  152, 2019. 

39.  方诩. 生物质降解酶生产菌株的育种和应用.  生物产业技术,  2017. 

40.  方诩. N2O emission and bacterial community dynamics.  RSC advances,  2018. 

41.  方诩. Identification of a thermostable fungal lytic polysaccharide monooxygenase and evaluation of its effect on lignocellulosic degradation.  Applied Microbiology and Biotechnology,  103,  5739, 2019. 

42.  方诩  and 王明钰. Regulation of cellulase expression, sporulation, and morphogenesis by velvet family proteins in Trichoderma reesei.  Appl Microbiol Biotechnol,  100,  769, 2016. 

43.  方诩 , 王明钰  and 戴莉. The structural and biochemical basis for cellulose biodegradation.  Journal of Industrial Technology and Biotechnology,  88,  491, 2013. 

44.  方诩 , 王方忠  and 王明钰. Function of a p24 Heterodimer in Morphogenesis and Protein Transport in Penicillium oxalicum.  scientific reports,  5,  11875, 2015. 

45.  方诩. Functional diversity of the p24 homologue Erp reveals physiological differences between two filamentous fungi.  Fungal Genetics and Biology,  61,  22,

46.  方诩 , 王明钰 , 王海龙 , 张友明  and 王方忠. A Tet-on and Cre-loxP Based Genetic Engineering System for Convenient Recycling of Selection Markers in Penicillium oxalicum.  Frontiers in Microbiology,  7,  485, 2016. 

47.  曲音波  and 方诩. Long-term strain improvements accumulate mutations in regulatory elements responsible for hyper-production of cellulolytic enzymes.  scientific reports,  2013. 

48.  王明钰 , 方诩 Identification of the role of a MAP kinase Tmk2 in Hypocrea jecorina (Trichoderma reesei).  Scientific Reports,  4,  6732, 2014. 

49.  方诩 , 王明钰  and 侯少莉. 里氏木霉纤维素酶生产工艺的优化.  黑龙江农业科学,  2012,  108, 2012. 

50.  王明钰 , 方诩 Factors involved in the response to improvement of agitation during cellulase production from Penicillium decumbens JUA10-1.  Journal of Industrial Microbiology & Biotechnology,  40,  1077, 2013. 

51.  王明钰 , 方诩 Contributing factors in the improvements of cellulosic H2 production in Clostridium thermocellum/Thermoanaerobacterium co-cultures.  Applied Microbiology and Biotechnology,  100,  8607, 2016. 

52.  王明钰 , 罗毅  and 方诩. Functional analysis of Trichoderma reesei CKIIα2, a catalytic subunit of casein kinase II.  Applied Microbiology and Biotechnology,  99,  5929, 2015. 

53.  王明钰 , 杨静华 , 孙孝敏 , 方诩 A Weibull statistics-based lignocellulose saccharification model and a built-in parameter accurately predict lignocellulose hydrolysis performance.  Biotechnology Journal,  10,  1424, 2015. 

54.  方诩 , 王明钰  and 王方忠. Regulation of cellulase expression, sporulation and morphogenesis by velvet family proteins in Trichoderma reesei.  Applied Microbiology and Biotechnology,  100,  769, 2016. 

55.  方诩 , 王明钰 , 贾春江  and Yong Yi. An environmentally friendly and productive process for bioethanol production from potato waste.  Biotechnology for Biofuels,  9,  50, 2016. 

56.  曲音波 , 王禄山 , 王明钰  and 方诩. Cellulolytic enzyme production and enzymatic hydrolysis for second-generation biofuel production.  Advances in Biochemical Engineering-Biotechnology,  128,  1, 2012. 

57.  方诩 , 王明钰  and 张杰. Efficient acetone-butanol-ethanol production from corncob with a new pretreatment technology - wet disk milling.  Bioenergy Research,  6,  35, 2013. 

58.  方诩 , 王明钰  and 王俊丽. The identification of and relief from Fe3+ inhibition for both cellulose and cellulase in cellulose saccharification catalyzed by cellulases from Penicillium decumbens.  Bioresource Technology,  133,  507, 2013. 

59.  方诩 , 杨静华 , 王明钰  and 姜宝杰. A mitogen-activated protein kinase Tmk3 participates in high osmolarity resistance, cell wall integrity maintenance and cellulase production regulation in Trichoderma reesei.  PLoS ONE,  8,  e72189, 2013. 

60.  方诩 , 王明钰  and 自振滔. 利用等离子诱变技术改造纤维素酶生产丝状真菌工业菌株.  中国酿造,  32,  5, 2013. 

61.  方诩 , 王明钰  and 杨惠. Functional diversity of the p24γ homologue Erp reveals physiological differences between two filamentous fungi.  Fungal Genetics and Biology,  61,  15, 2013. 

62.  徐孝刚 , 方诩 , 沈煜 , 魏天迪 , 王明钰  and 邵明. 山东大学生物类拔尖人才培养模式的探索.  高校生物学教学研究(电子版),  3,  3, 2013. 

63.  方诩 , 王明钰  and 王方忠. 丝状真菌中纤维素酶与半纤维素酶的合成调控.  生物加工过程,  12,  72, 2014. 

64.  方诩 , 王明钰  and 张晓东. 以木质纤维素原料生产生物丁醇的研究进展.  生物产业技术,  2014,  59, 2014. 

65.  方诩  and 王明钰. Efficient acetone-butanol-ethanol production from corncob with a new pretreatment technology - wet disk milling.  Bioenergy research,  6,  35-43, 2013. 

66.  方诩 , 王方忠  and 王明钰. Functional diversity of the p24 homologue Erp reveals physiological differences between two filamentous fungi.  Fungal Genetics and Biology,  61,  15, 2013. 

67.  方诩 , 曲音波 , 沈煜 , 赵建  and 鲍晓明. Status and Prospect of Lignocellulosic Bioethanol Production in China.  Bioresource technology,  101,  4814, 2010. 

68.  XWFZR , 方诩  and 校外负责人. Microbial lipid production by the oleaginous yeast Cryptococcus curvatus O3 grown in fed-batch culture.  Biomass and Bioenergy,  35,  1906, 2011. 

69.  方诩 , 王方忠  and 王明钰. 丝状真菌中纤维素酶与半纤维素酶的合成调控.  《生物加工过程》,  12,  72, 2014. 

70.  方诩. An environmentally friendly and productive process for bioethanol production from potato waste .  Biotechnology for biofuels,  9,  50,

71.  李雪芝 , 林建强 , 方诩  and 曲音波. High concentration ethanol production from corncob residues by fed-batch strategy.  Bioresource technology,  101,  4952, 2010. 

72.  方诩 , 李忠海 , 王明钰  and 曲音波. 斜卧青霉去泛素化蛋白酶CREB 的缺失提高纤维素酶的生产.  《生物工程学报》,  28,  959, 2012. 

73.  方诩  and 王明钰. 里氏木霉纤维素酶生产工艺的优化.  黑龙江农业科学,  2012,  108, 2012. 

74.  方诩 , 王明钰  and 曲音波. 斜卧青霉转录调控因子BglR的缺失对纤维素酶生产的影响.  《微生物学通报》,  39,  1379, 2012. 

75.  XWFZR , 方诩  and 校外负责人. Production and characterization of cellulases and hemicellulases by Acremonium cellulolyticus using rice straw subjected to various pretreatments as the carbon source.  Enzyme and Microbial Technology,  48,  162, 2011. 

76.  方诩 , 宋海波 Irisin reverses platelet derived growth factor-BB-induced vascular smooth muscle cells phenotype modulation through STAT3 signaling pathway.  Biochemical and biophysical research communications,  479,  139, 2016. 

77.  方诩  and 王方忠. An environmentally friendly and productive process for bioethanol production from potato waste.  Biotechnology for biofuels,  9,  50, 2016. 

78.  方诩  and 王明钰. 利用等离子诱变技术改造纤维素酶生产丝状真菌工业菌株.  中国酿造,  32,  2013. 

79.  方诩 , 曲音波 , 秦玉琪 , 李雪芝 , 王禄山 , 汪天虹  and 朱明田. 纤维素酶与木质纤维素生物降解转化的研究进展.  《生物工程学报》,  2010. 

80.  倪寿清 , 崔兆杰 , 方诩  and 郭蓓蓓. Transformation of the zero valent iron dosage effect on anammox after long-term culture: From inhibition to promotion.  Process biochemistry,  78,  132, 2019. 

81.  倪寿清 , 徐世平 , 方诩 , 占金华 , 张烁烁 One-pot synthesis of highly active Ni/Fe nano-bimetal by simultaneous ball milling and in situ chemical deposition.  RSC advances,  8,  26469, 2018. 

82.  徐世平 , 方诩  and 占金华. One-pot synthesis of highly active Ni/Fe nano-bimetal by simultaneous ball milling and in situ chemical deposition.  RSC Advances,  2018. 

83.  倪寿清 , 徐世平  and 方诩. One-pot synthesis of highly active Ni/Fe nano-bimetal by simultaneous ball milling and in situ chemical deposition.  RSC advances,  2018. 

84.  沈煜  and 方诩. Rational Engineering of Chorismate-Related Pathways in Saccharomyces cerevisiae for Improving Tyrosol Production.  Frontiers in Bioengineering and Biotechnology,  7,  152, 2019. 

85.  方诩. 生物质降解酶生产菌株的育种和应用.  生物产业技术,  2017. 

86.  方诩. N2O emission and bacterial community dynamics.  RSC advances,  2018. 

87.  方诩. Identification of a thermostable fungal lytic polysaccharide monooxygenase and evaluation of its effect on lignocellulosic degradation.  Applied Microbiology and Biotechnology,  103,  5739, 2019. 

88.  方诩  and 戴莉. The structural and biochemical basis for cellulose biodegradation.  88,  491, 2013. 

89.  方诩  and 侯少莉. 里氏木霉纤维素酶生产工艺的优化.  2012,  108, 2012. 

90.  方诩  and 王方忠. Regulation of cellulase expression, sporulation and morphogenesis by velvet family proteins in Trichoderma reesei.  100,  769, 2016. 

91.  方诩  and Yong Yi. An environmentally friendly and productive process for bioethanol production from potato waste.  9,  50, 2016. 

92.  方诩  and 张杰. Efficient acetone-butanol-ethanol production from corncob with a new pretreatment technology - wet disk milling.  6,  35, 2013. 

93.  方诩  and 王俊丽. The identification of and relief from Fe3+ inhibition for both cellulose and cellulase in cellulose saccharification catalyzed by cellulases from Penicillium decumbens.  133,  507, 2013. 

94.  方诩  and 自振滔. 利用等离子诱变技术改造纤维素酶生产丝状真菌工业菌株.  32,  5, 2013. 

95.  方诩  and 杨惠. Functional diversity of the p24γ homologue Erp reveals physiological differences between two filamentous fungi.  61,  15, 2013. 

96.  方诩  and 邵明. 山东大学生物类拔尖人才培养模式的探索.  3,  3, 2013. 

97.  方诩  and 校外负责人. Microbial lipid production by the oleaginous yeast Cryptococcus curvatus O3 grown in fed-batch culture.  Biomass and Bioenergy,  35,  1906, 2011. 

98.  李雪芝 , 林建强 , 方诩  and 曲音波. High concentration ethanol production from corncob residues by fed-batch strategy.  Bioresource technology,  101,  4952, 2010. 

99.  方诩  and 校外负责人. Production and characterization of cellulases and hemicellulases by Acremonium cellulolyticus using rice straw subjected to various pretreatments as the carbon source.  Enzyme and Microbial Technology,  48,  162, 2011. 

100.  沈煜 , 徐孝刚 , 邵明 , 魏天迪 , 方诩  and 王明钰. 山东大学生物类拔尖人才培养模式的探索.  高校生物学教学研究(电子版),  3,  3, 2013. 

101.  王明钰 , 方诩  and 自振滔. 利用等离子诱变技术改造纤维素酶生产丝状真菌工业菌株.  中国酿造,  32,  5, 2013. 

102.  方诩  and 王明钰. Role of Trichoderma reesei mitogen-activated protein kinases (MAPKs) in cellulase formation.  Biotechnology for biofuels,  10,  99, 2017. 

103.  方诩  and 王明钰. Identification of the role of a MAP kinase Tmk2 in Hypocrea jecorina (Trichoderma reesei).  4,  6732, 2014. 

104.  方诩  and 王明钰. Factors involved in the response to improvement of agitation during cellulase production from Penicillium decumbens JUA10-1.  40,  1077, 2013. 

105.  方诩  and 王明钰. Contributing factors in the improvements of cellulosic H2 production in Clostridium thermocellum/Thermoanaerobacterium co-cultures.  100,  8607, 2016. 

106.  罗毅 , 方诩  and 王明钰. Functional analysis of Trichoderma reesei CKIIα2, a catalytic subunit of casein kinase II.  99,  5929, 2015. 

107.  杨静华 , 孙孝敏 , 方诩  and 王明钰. A Weibull statistics-based lignocellulose saccharification model and a built-in parameter accurately predict lignocellulose hydrolysis performance.  10,  1424, 2015. 

108.  倪寿清 , 崔兆杰 , 方诩  and 郭蓓蓓. Transformation of the zero valent iron dosage effect on anammox after long-term culture: From inhibition to promotion.  Process biochemistry,  78,  132, 2019. 

109.  李雪芝 , 林建强 , 方诩  and 曲音波. High concentration ethanol production from corncob residues by fed-batch strategy.  Bioresource technology,  101,  4952, 2010. 

110.  王明钰 , 杨静华 , 方诩  and 姜宝杰. A mitogen-activated protein kinase Tmk3 participates in high osmolarity resistance, cell wall integrity maintenance and cellulase production regulation in Trichoderma reesei.  8,  e72189, 2013. 

111.  徐世平 , 方诩 , 占金华  and 张烁烁. One-pot synthesis of highly active Ni/Fe nano-bimetal by simultaneous ball milling and in situ chemical deposition.  RSC advances,  8,  26469, 2018. 

112.  魏天迪 , 徐孝刚 , 王明钰 , 沈煜 , 方诩  and 邵明. 山东大学生物类拔尖人才培养模式的探索.  3,  3, 2013. 

113.  杨静华 , 王明钰 , 方诩 , 孙孝敏  and 赵雪兵. A Weibull statistics-based lignocellulose saccharification model and a built-in parameter accurately predict lignocellulose hydrolysis performance.  10,  1424, 2015. 

114.  王明钰 , 王海龙 , 张友明 , 方诩  and 刘奎美. A Tet-on and Cre-loxP based genetic engineering system for convenient recycling of selection markers in Penicillium oxalicum.  7,  486, 2016. 

115.  贾春江 , 王明钰 , 方诩  and Yong Yi. An environmentally friendly and productive process for bioethanol production from potato waste.  9,  50, 2016. 

116.  方诩  and 校外负责人. Production and characterization of cellulases and hemicellulases by Acremonium cellulolyticus using rice straw subjected to various pretreatments as the carbon source.  Enzyme and Microbial Technology,  48,  162, 2011. 

117.  方诩  and 校外负责人. Microbial lipid production by the oleaginous yeast Cryptococcus curvatus O3 grown in fed-batch culture.  Biomass and Bioenergy,  35,  1906, 2011. 

118.  王明钰 , 方诩  and 赵秋爽. Identification of the role of a MAP kinase Tmk2 in Hypocrea jecorina (Trichoderma reesei).  4,  6732, 2014. 

119.  王明钰 , 方诩  and 牛康乐. Contributing factors in the improvements of cellulosic H2 production in Clostridium thermocellum/Thermoanaerobacterium co-cultures.  100,  8607, 2016. 

120.  王明钰 , 方诩  and 王方忠. Regulation of cellulase expression, sporulation and morphogenesis by velvet family proteins in Trichoderma reesei.  100,  769, 2016. 

121.  沈煜 , 赵建 , 鲍晓明 , 曲音波  and 方诩. Status and Prospect of Lignocellulosic Bioethanol Production in China.  Bioresource technology,  101,  4814, 2010. 

122.  曲音波 , 王禄山 , 王明钰  and 方诩. Cellulolytic enzyme production and enzymatic hydrolysis for second-generation biofuel production.  128,  1, 2012. 

123.  方诩. An environmentally friendly and productive process for bioethanol production from potato waste .  Biotechnology for biofuels,  9,  50,

124.  方诩. Functional diversity of the p24 homologue Erp reveals physiological differences between two filamentous fungi.  Fungal Genetics and Biology,  61,  22,

125.  王方忠  and 方诩. An environmentally friendly and productive process for bioethanol production from potato waste.  Biotechnology for biofuels,  9,  50, 2016. 

126.  方诩. Irisin reverses platelet derived growth factor-BB-induced vascular smooth muscle cells phenotype modulation through STAT3 signaling pathway.  Biochemical and biophysical research communications,  479,  139, 2016. 

127.  曲音波  and 方诩. Long-term strain improvements accumulate mutations in regulatory elements responsible for hyper-production of cellulolytic enzymes.  scientific reports,  2013. 

128.  王方忠 , 王明钰 , 王海龙 , 张友明  and 方诩. A Tet-on and Cre-loxP Based Genetic Engineering System for Convenient Recycling of Selection Markers in Penicillium oxalicum.  Frontiers in Microbiology,  7,  485, 2016. 

129.  王明钰  and 方诩. Regulation of cellulase expression, sporulation, and morphogenesis by velvet family proteins in Trichoderma reesei.  Appl Microbiol Biotechnol,  100,  769, 2016. 

130.  王方忠 , 王明钰  and 方诩. Function of a p24 Heterodimer in Morphogenesis and Protein Transport in Penicillium oxalicum.  scientific reports,  5,  11875, 2015. 

131.  王明钰  and 方诩. 利用等离子诱变技术改造纤维素酶生产丝状真菌工业菌株.  中国酿造,  32,  2013. 

132.  王方忠 , 王明钰  and 方诩. 丝状真菌中纤维素酶与半纤维素酶的合成调控.  《生物加工过程》,  12,  72, 2014. 

133.  王明钰  and 方诩. Efficient acetone-butanol-ethanol production from corncob with a new pretreatment technology - wet disk milling.  Bioenergy research,  6,  35-43, 2013. 

134.  王明钰 , 曲音波  and 方诩. 斜卧青霉转录调控因子BglR的缺失对纤维素酶生产的影响.  《微生物学通报》,  39,  1379, 2012. 

135.  李忠海 , 王明钰 , 曲音波  and 方诩. 斜卧青霉去泛素化蛋白酶CREB 的缺失提高纤维素酶的生产.  《生物工程学报》,  28,  959, 2012. 

136.  王明钰  and 方诩. 里氏木霉纤维素酶生产工艺的优化.  黑龙江农业科学,  2012,  108, 2012. 

137.  秦玉琪 , 李雪芝 , 王禄山 , 汪天虹 , 朱明田 , 曲音波  and 方诩. 纤维素酶与木质纤维素生物降解转化的研究进展.  《生物工程学报》,  2010. 

138.  王明钰 , 方诩  and 王俊丽. The identification of and relief from Fe3+ inhibition for both cellulose and cellulase in cellulose saccharification catalyzed by cellulases from Penicillium decumbens.  133,  507, 2013. 

139.  王明钰 , 方诩  and 侯少莉. Factors involved in the response to improvement of agitation during cellulase production from Penicillium decumbens JUA10-1.  40,  1077, 2013. 

140.  王明钰 , 方诩  and 杨惠. Functional diversity of the p24γ homologue Erp reveals physiological differences between two filamentous fungi.  61,  15, 2013. 

141.  王明钰 , 方诩  and 自振滔. 利用等离子诱变技术改造纤维素酶生产丝状真菌工业菌株.  32,  5, 2013. 

142.  方诩. N2O emission and bacterial community dynamics.  RSC advances,  2018. 

143.  方诩. 生物质降解酶生产菌株的育种和应用.  生物产业技术,  2017. 

144.  倪寿清 , 徐世平  and 方诩. One-pot synthesis of highly active Ni/Fe nano-bimetal by simultaneous ball milling and in situ chemical deposition.  RSC advances,  2018. 

145.  方诩 , 王明钰  and 侯少莉. 里氏木霉纤维素酶生产工艺的优化.  2012,  108, 2012. 

146.  罗毅 , 方诩 , 王明钰  and 张美玲. Functional analysis of Trichoderma reesei CKIIα2, a catalytic subunit of casein kinase II.  99,  5929, 2015. 

147.  方诩 , 王明钰 , 曲音波  and 周广麒. 斜卧青霉去泛素化蛋白酶CREB的缺失提高纤维素酶的生产.  28,  959, 2012. 

148.  王明钰  and 方诩. Function of a p24 heterodimer in morphogenesis and protein transport in Penicillium oxalicum.  5,  11875, 2015. 

149.  方诩 , 王明钰  and 戴莉. The structural and biochemical basis for cellulose biodegradation.  88,  491, 2013. 

150.  方诩 , 王明钰  and 张晓东. 以木质纤维素原料生产生物丁醇的研究进展.  2014,  59, 2014. 

151.  王明钰  and 方诩. Role of Trichoderma reesei mitogen-activated protein kinases (MAPKs) in cellulase formation.  Biotechnology for biofuels,  10,  2017. 

专利
科研项目

1. 非细胞生物合成系统的构建与应用, 2019/07/01-2024/06/30

2. 农业秸秆高效预处理及酶解关键技术, 2019/04/08-2023/03/31

3. 第二代燃料乙醇生产集成技术研究, 2010/01/01-2012/12/31

4. 产酪醇酿酒酵母细胞工厂的构建和优化, 2018/06/22-2020/12/31

5. 热纤梭菌中的Ech氢酶性质研究, 2012/07/31-2015/07/31

6. 纤维素酶的研究, 2011/02/20-2013/12/31

7. 真菌纤维素酶与木质素非产出性吸附的分子机理研究及纤维素酶的改造, 2018/08/16-2022/12/31

8. 非粮生物质制备燃料乙醇关键技术的研发, 2017/12/31-2021/12/31

9. 生物降解生物质制备乙醇技术, 2017/12/01-2019/12/31

10. 厌氧氨氧化过程中的生物调控机制, 2016/01/01-2018/12/01

11. K—微生物技术国家重点实验室成果奖励, 2016/12/01-2017/12/31

12. K-微生物技术国家重点实验室开放运行费自主设置课题07, 2016/07/01-2017/12/31

13. Y-里氏木霉中木质纤维素复合体的结构和性质, 2016/03/29-2017/12/31

14. 先进酶制剂生产技术的研究及应用, 2015/07/01-2017/09/30

15. 里氏木霉中酪蛋白激酶II在纤维素酶表达调控中的作用及调控机制的研究, 2015/08/17-2019/12/31

16. Y-酪蛋白激酶II在里氏木霉纤维素酶表达调控中的功能及其分子机制的研究, 2015/07/01-2017/12/31

17. 新型木质纤维素酶系生产制备及产业化开发, 2014/10/01-2017/12/31

18. K-酪蛋白激酶II在里氏木霉纤维素酶表达调控中的功能及其分子机制的研究, 2015/01/01-2016/12/31

19. 复合纤维素酶菌种生产工艺及薯渣制糖, 2014/04/08-2016/04/07

20. 万吨级纤维素乙醇生产关键技术研究及示范-3, 2013/01/01-2015/12/31

21. 木质纤维素酶水解过程中酶吸附?解吸附分子机理的研究, 2013/10/01-2016/10/31

22. 高产纤维素酶菌株选育和发酵技术优化, 2013/01/01-2017/12/31

23. 新型木质纤维素酶系生产制备, 2012/01/01-2015/12/31

24. 纤维素酶高产菌株的育种与纤维素酶生产工艺的优化, 2012/03/01-2013/12/31

25. 木素纤维素乙醇生产关键技术研究二, 2009/10/26-2010/12/31

26. 2011年度国家重点实验室成果奖励方诩, 2011/01/01-2011/12/31

27. 运行费-微生物重点实验自主设置课题06(2010年第二批), 2010/01/01-2010/12/31

28. 棕榈生物质乙醇转化研究-2, 2010/01/01-2012/12/31

29. 2011年度国家重点实验室成果奖励方诩-运行费, 2011/01/01-2011/12/31

30. (科研业务费)微生物重点实验室引进人才科研费, 2010/01/01-2011/12/31

31. 微生物重点实验室引进人才科研费, 2009/01/01-2011/12/31

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