Professor
姜新义，山东大学药学院/齐鲁医院教授，博导，国家杰出青年基金获得者，国家重点研发计划首席科学家，国际先进材料协会会士，担任山东省靶向递药与高端制剂重点实验室主任，山东省高等学校细胞治疗校企产学研协同创新中心主任，山东大学生物治疗研究中心主任。承担国家基金委重点项目、原创探索项目，国家重点研发计划重点项目等；相关研究发表于Nature Biotechnology，Cell stem Cell，Nature Cancer，Cell Host & Microbe，Nature Nanotechnology，PNAS等TOP期刊；申报国家发明专... More+
Paper Publications
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[1] . Implantable Microneedle-Mediated Eradication of Postoperative Tumor Foci Mitigates Glioblastoma Relapse. ADVANCED MATERIALS, 2024.
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[2] . mRNA-Laden Lipid-Nanoparticle-Enabled in Situ CAR-Macrophage Engineering for the Eradication of Multidrug-Resistant Bacteria in a Sepsis Mouse Model. ACS nano, 18, 2261-2278, 2024.
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[3] . Stimulation of tumoricidal immunity via bacteriotherapy inhibits glioblastoma relapse. NATURE COMMUNICATIONS, 15, 2024.
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[4] . Realveolarization with inhalable mucus-penetrating lipid nanoparticles for the treatment of pulmonary fibrosis in mice. Science Advances, 10, 2024.
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[5] . Intracavitary Spraying of Nanoregulator-Encased Hydrogel Modulates Cholesterol Metabolism of Glioma-Supportive Macrophage for Postoperative Glioblastoma Immunotherapy. ADVANCED MATERIALS, 2023.
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[6] . Trojan Horse Nanocapsule Enabled In Situ Modulation of the Phenotypic Conversion of Th17 Cells to Treg Cells for the Treatment of Multiple Sclerosis in Mice. ADVANCED MATERIALS, 35, 2023.
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[7] . Intracavity generation of glioma stem cell–specific CAR macrophages primes locoregional immunity for postoperative glioblastoma therapy. SCIENCE TRANSLATIONAL MEDICINE, 2022.
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[8] . Cell membrane derived liposomes loaded with DNase I target neutrophil extracellular traps which inhibits colorectal cancer liver metastases. Journal of Controlled Release, 357, 620-629, 2023.
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[9] . Remodeling articular immune homeostasis with an efferocytosis-informed nanoimitator mitigates rheumatoid arthritis in mice. NATURE COMMUNICATIONS, 14, 2023.
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[10] . In situ MUC1-specific CAR engineering of tumor-supportive macrophages stimulates tumoricidal immunity against pancreatic adenocarcinoma. NANO TODAY, 49, 2023.
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[11] . Metabolic Modulation of Intracellular Ammonia via Intravesical Instillation of Nanoporter-Encased Hydrogel Eradicates Bladder Carcinoma. Advanced Science, 10, 2023.
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[12] . Leveraging tumor cell ferroptosis for colorectal cancer treatment via nanoelicitor-activated tumoricidal immunity. Chemical Engineering Journal, 430, 2022.
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[13] . Inhaled mRNA Nanoformulation with Biogenic Ribosomal Protein Reverses Established Pulmonary Fibrosis in a Bleomycin-Induced Murine Model. ADVANCED MATERIALS, 34, e2107506, 2022.
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[14] . Bioinspired nano-painting on orthopedic implants orchestrates periprosthetic anti-infection and osseointegration in a rat model of arthroplasty. Chemical Engineering Journal, 435, 2022.
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[15] 刘毅. Galectin-1 inhibited LPS-induced autophagy and apoptosis of human periodontal ligament stem cells. Inflammation, 44, 1302, 2021.
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[16] 高琼琼. Reply to "Comment on 'In Situ Mannosylated Nanotrinity-Mediated Macrophage Remodeling Combats Candida Albicans Infection"'. ACS nano, 15, 3544, 2021.
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[17] Abdalla, Mohnad. Progress in research on the S protein as the target of COVID-19 vaccines. EXPERT REVIEW OF VACCINES, 2021.
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[18] 张晶. Immunostimulant hydrogel for the inhibition of malignant glioma relapse post-resection. NATURE NANOTECHNOLOGY, 2021.
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[19] Kong, Degang. Chemoembolizing hepatocellular carcinoma with microsphere cored with arsenic trioxide microcrystal. Drug Delivery, 27, 1729, 2020.
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[20] 陈晨. In situ tuning proangiogenic factor-mediated immuno-tolerance synergizes the tumoricidal immunity via a hypoxia-triggerable liposomal bio-nanoreactor. THERANOSTICS, 10, 11998, 2020.