Jiang Xinyi
Professor
姜新义，山东大学药学院/齐鲁医院教授，博导，国家杰出青年基金获得者，国家高层次青年人才，国家重点研发计划首席科学家，国家高层次青年人才，国际先进材料协会会士，国家药监局创新药物临床研究与评价重点实验室副主任，山东省靶向递药与高端制剂重点实验室主任，“智能材料与药物精准递送”团队PI。先后承担国家基金委原创探索、国合重点项目，国家重点研发计划重点项目，山东省重点、重大项目等20余项；在Nature Cancer，Science Translational Medicine，Nature Nanotechnolo... More+
Scientific Research
Working-Papers
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Paper Publications
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. Implantable Microneedle-Mediated Eradication of Postoperative Tumor Foci Mitigates Glioblastoma Relapse. ADVANCED MATERIALS, 2024.
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. mRNA-Laden Lipid-Nanoparticle-Enabled in Situ CAR-Macrophage Engineering for the Eradication of Multidrug-Resistant Bacteria in a Sepsis Mouse Model. ACS nano, 18, 2261-2278, 2024.
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. Stimulation of tumoricidal immunity via bacteriotherapy inhibits glioblastoma relapse. NATURE COMMUNICATIONS, 15, 2024.
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. Realveolarization with inhalable mucus-penetrating lipid nanoparticles for the treatment of pulmonary fibrosis in mice. Science Advances, 10, 2024.
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. Intracavitary Spraying of Nanoregulator-Encased Hydrogel Modulates Cholesterol Metabolism of Glioma-Supportive Macrophage for Postoperative Glioblastoma Immunotherapy. ADVANCED MATERIALS, 2024.
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. Trojan Horse Nanocapsule Enabled In Situ Modulation of the Phenotypic Conversion of Th17 Cells to Treg Cells for the Treatment of Multiple Sclerosis in Mice. ADVANCED MATERIALS, 35, 2023.
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. Intracavity generation of glioma stem cell–specific CAR macrophages primes locoregional immunity for postoperative glioblastoma therapy. SCIENCE TRANSLATIONAL MEDICINE, 2023.
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. Cell membrane derived liposomes loaded with DNase I target neutrophil extracellular traps which inhibits colorectal cancer liver metastases. Journal of Controlled Release, 357, 620-629, 2023.
Patents
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Research Projects
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泌尿男生殖系疾病精准诊疗工程研究中心 , 2025-01-01 -2027-12-31
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巨噬细胞时空可控工程化改造关键技术及转化应用研究 , 2024-12-01 -2029-11-30
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巨噬细胞时空可控工程化改造关键技术及转化应用研究 , 2024-12-01 -2029-11-30
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（包干项目）核酸递释载体与成药性 , 2024-08-23 -2029-12-31
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CAR-巨噬细胞在体编辑载体及内吞增效机制研究 , 2023-12-28 -2026-12-31
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纳米肿瘤疫苗关键科学问题及设计原理研究 , 2023-01-01 -2025-12-31
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基于“肿瘤芯片”的siRNA纳米制剂优化及其调控胆固醇代谢治疗脑胶质瘤机制研究 , 2021-12-13 -2024-09-30
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重大核酸创新药物靶向递送载体关键技术研究与开发 , 2021-10-29 -2024-12-31
Research Team
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