Jiang Xukai
Associate Professor
蒋绪恺，副研究员/博士生导师，泰山学者青年专家、山东省海外优青；中国药学会智能药物专业委员会青年委员、中国药理学会海洋药物药理专业委员会青年委员、山东省生物化学与分子生物学学会理事。主要从事细胞膜系统的结构-动态-功能研究、细胞膜靶向药物设计与作用机制研究，构建了革兰氏阴性细菌和人体肠道、肾脏、肺泡、皮肤、血脑屏障等结构数字孪生模型，用于抗菌药物、抗肿瘤药物、神经系统药物等的设计与研发。以第一/通讯（含共同）在Nature Communications、Advanced Scien... More+
Scientific Research
Working-Papers
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Paper Publications
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许立美. Interaction of polyethylene nanoplastics with the plasma, endoplasmic reticulum, Golgi apparatus, lysosome and endosome membranes: A molecular dynamics study. Ecotoxicology and Environmental Safety, 118680, 2025.
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崔錾. In Silico-Guided Discovery of Polysaccharide Derivatives as Adjuvants in Nanoparticle Vaccines for Cancer Immunotherapy. ACS nano, 2025.
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马振宇. Membrane lipid homeostasis dually regulates conformational transition of phosphoethanolamine transferase EptA. NATURE COMMUNICATIONS, 15, 2025.
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刘卓. Enhanced Sampling Molecular Dynamics Simulations Reveal Transport Mechanism of Glycoconjugate Drugs through GLUT1. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 2024.
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. Engineering the substrate preference of glucose oxidase for the enzymatic oxidation of xylose. GREEN CHEMISTRY, 26, 4851, 2024.
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朱景一. Molecular Dynamics Simulations Reveal Octanoylated Hyaluronic Acid Enhances Liposome Stability, Stealth and Targeting. ACS Omega, 2025.
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赵沙. Engineering the Relatively Conserved Residues in Active Site Architecture of Thermophilic Chitinase SsChi18A Enhanced Catalytic Activity. Biomacromolecules, 25, 2024.
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蒋绪恺. Structure-Interaction Relationship of Polymyxins with Lung Surfactant. Journal of Medicianal Chemistry, 66, 16109-16119, 2024.
Patents
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Published Books
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Research Projects
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2类改良型新药格隆溴铵福莫特罗吸入粉雾剂关键技术开发及评价研究, 2025-06-01-2027-05-31
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微生物技术国家重点实验室科普宣讲团, 2024-01-01-2024-10-30
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木质素定向解聚限速酶分子基础及设计改造子课题, 2023-12-01-2028-11-30
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药物与人体肺呼吸道互作评价研究, 2023-12-08-2024-12-31
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半乳糖基转移酶计算设计, 2023-12-06-2024-05-31
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长效注射剂体外质量评价, 2023-12-06-2024-02-28
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（包干项目）脂多糖修饰酶EptA对细胞膜脂质相分离的响应机制研究, 2023-08-24-2026-12-31
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（包干项目）细胞膜系统与抗生素智能设计, 2023-01-01-2025-12-31
Research Team
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