Prof. Lei Zhang is a distinguished professor at the School of Public Health, Shandong University. He is the director and principal investigator of the Microbiome-X center at the National Institute of Health Data Science of China, as well as the principal investigator at the State Key Laboratory of Microbial Technology, Shandong University. He also serves as the president of the Shandong Institute of Industrial Technology for Healthy Sciences and Precision Medicine, and the deputy director of the Shandong Children's Microbiology Research Center at the Qilu Children’s Hospital of Shandong University. Prof. Zhang received his Ph.D. in Microbiology at the University of Bremen, Germany (2005). After his postdoctoral training at UCLA (2008). He was hired as Research Assistant Professor by UCLA since 2008 and principal investigator since 2010. Prof. Zhang focus on microbiome research. As the principal investigator of two research programs founded by TRDRP (Tobacco-Related Disease Research Program) and CBCRP (California Breast Cancer Research Program), he led multi-center studies that revealed the relationship between salivary microbiome and multiple cancers (Gut, 2012; Gastroenterology, 2010, and other 25 articles). At Shandong University, he initiated Shandong Microbiome Research Project, established a cross-regional 10,000+ cohort, and constructed a standardized biobank, mostly Type 2 Diabetes. He also built up the largest standardized microbiome data set in the National Omics Data Encyclopedia (NODE). Most importantly, he led the microbiome studies to decipher the "correlation→causality→intervention" in various diseases including T2D. In the past five years, his team have published 32 articles in Gut, 2021; mSystems, 2020; GPB, 2019; Microbiome, 2018, etc., and obtained 4 patents.