liu lei
Professor
刘磊，男，1981年生，教授、博士生导师，学院副院长 入选国家杰青、国家优青、泰山学者特聘专家、教育部新世纪优秀人才、山东省杰青、山东大学齐鲁青年学者 学术任职：任 中国化学会有机化学学科委员会委员（2022-）、 Chin. Chem. Lett.编委（2021-）、《有机化学》青年编委（2019-） 研究方向：仿生不对称氧化、复杂分子不对称合成、抗菌金属药物化学生物学 邮箱：leiliu@sdu.edu.cn 地址：山东省济南市历城区山大南路27号山东大学老数学楼113 课题组英文主页：http://leiliugro... More+
Scientific Research
Working-Papers
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Paper Publications
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关弘浩. Methane Monooxygenase Mimic Asymmetric Oxidation: Self-Assembling μ-Hydroxo, Carboxylate-Bridged Diiron(III)-Catalyzed Enantioselective Dehydrogenation. J. Am. Chem. Soc. , 2024.
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. Site- and Enantiodifferentiating C(sp3)–H Oxidation Enables Asymmetric Access to Structurally and Stereochemically Diverse Saturated Cyclic Ethers. J. Am. Chem. Soc. , 2024.
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曹敏. Site- and Enantioselective Manganese-Catalyzed Benzylic C–H Azidation of Indolines. J. Am. Chem. Soc. , 2024.
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. Catalytic Enantioselective Hydroxylation of Tertiary Propargylic C(sp3)-H Bonds in Acyclic Systems: a Kinetic Resolution Study. Journal of the American Chemical Society, 146, 2024.
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李松. Late-Stage Chemo- and Enantioselective Oxidation of Indoles to C3-Monosubstituted Oxindoles. Journal of the American Chemical Society, 145, 27120-27130, 2024.
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王岗. Catalytic Asymmetric Oxidation of Amines to Hydroxylamines. J. AM. CHEM. SOC., 145, 22276, 2024.
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Du, Tianxing. Copper-Catalyzed [3 + 2 + 1] Cycloaddition of Alkenes with Benzoquinones and Dicarbonyl Compounds via Tandem Oxidative Dicarbofunctionalization/Cyclization Sequence. Chinese Journal of Chemistry, 40, 1681-1686, 2023.
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秦静. Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway. Bioorg Med Chem., 55, 116594, 2023.
Patents
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Published Books
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Research Projects
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（包干项目）仿生不对称催化氧化, 2024-08-23-2029-12-31
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手性有机叠氮标准品的合成, 2023-12-14-2024-12-31
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系列糖类高级衍生物的制备和在生物医药领域的应用, 2023-12-04-2024-12-31
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抗肿瘤药物芦可替尼手性合成工艺研发, 2021-10-10-2026-10-09
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（包干项目）新型1,3,4，9-四氢吡喃[3,4-b]_吲哚类化合物基于PI3K/AKT/mTOR信号通路抗三阴性乳腺癌的作用及机制, 2022-01-01-2024-12-31
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H045 项目片段 2 委托工艺开发（L）, 2022-03-25-2027-03-24
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手性[N4]铁催化不对称脱氢反应, 2021-12-20-2024-09-30
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氮、磷、硅等杂原子手性中心的不对称氧化构筑, 2021-12-03-2024-12-31
Research Team
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